| Long name: |
FITC Conjugated, PCPTP1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PCPTP1 |
| Specificity: |
This is a highly specific antibody against PCPTP1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human PCPTP1 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ECPTP, Expressed primarily in the brain with weaker expression in other parts of the body, PCPTP1, PCPTP1 is a receptor-like molecule that is able to dephosphorylate MAPKs, PTPBR7 or PTPRQ, The alpha form is localized to the cell membrane, Three isoforms of PCPTP1 exist and are designated alpha, also known as PTPRR (Receptor-type tyrosine-protein phosphatase R), beta and gamma, cell differentiation, is a 657 amino acid protein that functions to sequester inactive mitogen-activated protein kinases (MAPKs) to the cytoplasm, oncogenic transformation and the mitotic cycle, thereby rendering them inactive, while the beta and gamma forms are localized to the perinuclear areas within the cytoplasm, The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
PTPBR7 PTP-SL EC-PTP PCPTP1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PCPTP1 Conjugated |
| Short name: |
FITC Conjugated, PCPTP1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, PCPTP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9680 |
| Gene: |
PTPRR |
More about : PTPRR |
| Long gene name: |
protein tyrosine phosphatase, receptor type R |
| Synonyms gene: |
PTPRQ |
| Locus: |
12q15 |
| Discovery year: |
1999-10-28 |
| GenBank acession: |
D64053 |
| Entrez gene record: |
5801 |
| Pubmed identfication: |
7557444 10393441 |
| RefSeq identity: |
NM_002849 |
| Classification: |
Protein tyrosine phosphatases, receptor type |
| Havana BLAST/BLAT: |
OTTHUMG00000169502 |