| Long name: |
ALEXA FLUOR 488 Conjugated, PCPTP1 Polyclonal Antibody |
| Also known as: |
Anti-PCPTP1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PCPTP1 |
| Specificity: |
This is a highly specific antibody against PCPTP1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PCPTP1 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
ECPTP, Expressed primarily in the brain with weaker expression in other parts of the body, PCPTP1, PCPTP1 is a receptor-like molecule that is able to dephosphorylate MAPKs, PTPBR7 or PTPRQ, The alpha form is localized to the cell membrane, Three isoforms of PCPTP1 exist and are designated alpha, also known as PTPRR (Receptor-type tyrosine-protein phosphatase R), beta and gamma, cell differentiation, is a 657 amino acid protein that functions to sequester inactive mitogen-activated protein kinases (MAPKs) to the cytoplasm, oncogenic transformation and the mitotic cycle, thereby rendering them inactive, while the beta and gamma forms are localized to the perinuclear areas within the cytoplasm, The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
PTPBR7 PTP-SL EC-PTP PCPTP1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PCPTP1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
PCPTP1 |
| Short name: |
PCPTP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, PCPTP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9680 |
| Gene: |
PTPRR |
More about : PTPRR |
| Long gene name: |
protein tyrosine phosphatase, receptor type R |
| Synonyms gene: |
PTPRQ |
| Locus: |
12q15 |
| Discovery year: |
1999-10-28 |
| GenBank acession: |
D64053 |
| Entrez gene record: |
5801 |
| Pubmed identfication: |
7557444 10393441 |
| RefSeq identity: |
NM_002849 |
| Classification: |
Protein tyrosine phosphatases, receptor type |
| Havana BLAST/BLAT: |
OTTHUMG00000169502 |