| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PCPTP1 |
| Specificity: |
This antibody reacts specifically with PCPTP1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PCPTP1 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ECPTP, Expressed primarily in the brain with weaker expression in other parts of the body, PCPTP1, PCPTP1 is a receptor-like molecule that is able to dephosphorylate MAPKs, PTPBR7 or PTPRQ, The alpha form is localized to the cell membrane, Three isoforms of PCPTP1 exist and are designated alpha, also known as PTPRR (Receptor-type tyrosine-protein phosphatase R), beta and gamma, cell differentiation, is a 657 amino acid protein that functions to sequester inactive mitogen-activated protein kinases (MAPKs) to the cytoplasm, oncogenic transformation and the mitotic cycle, thereby rendering them inactive, while the beta and gamma forms are localized to the perinuclear areas within the cytoplasm, The protein tyrosine phosphatase (PTP) family of proteins are signaling molecules that regulate processes such as cell growth |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PTPBR7 PTP-SL EC-PTP PCPTP1 |
| Also known as: |
PCPTP1 Polyclonal Antibody |
| Other name: |
Anti-PCPTP1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PCPTP1 |
| Short name: |
Anti-PCPTP1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PCPTP1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9680 |
| Gene: |
PTPRR |
More about : PTPRR |
| Long gene name: |
protein tyrosine phosphatase, receptor type R |
| Synonyms gene: |
PTPRQ |
| Locus: |
12q15 |
| Discovery year: |
1999-10-28 |
| GenBank acession: |
D64053 |
| Entrez gene record: |
5801 |
| Pubmed identfication: |
7557444 10393441 |
| RefSeq identity: |
NM_002849 |
| Classification: |
Protein tyrosine phosphatases, receptor type |
| Havana BLAST/BLAT: |
OTTHUMG00000169502 |