| Long name: |
Biotin Conjugated, OTP Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
OTP |
| Specificity: |
This is a highly specific antibody against OTP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human OTP |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
At early embryonic stages in mice, Containing a homeobox DNA-binding domain and a OAR domain, OTP (orthopedia homeobox) is a 325 amino acid nuclear protein belonging to the paired homeobox family and Bicoid subfamily, OTP is expressed in neurons, OTP is highly conserved in evolution and is encoded by a gene located on human chromosome 5, OTP is suggested to be involved in the differentiation of hypothalamic neuroendocrine cells, anterior periventricular (aPV) and arcuate (ARN) nuclei, indicating a potential role for OTP as an upstream regulator of SIM2, supraoptic (SON), the expression of SIM2 is downregulated in the absence of OTP, which contains 181 million base pairs and comprises nearly 6% of the human genome, which give rise to the paraventricular (PVN), Homeodomain (HD) genes are helix-turn-helix transcription factors that play key roles in the specification of cell fates |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
OTP Conjugated |
| Short name: |
Conjugated, OTP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, OTP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8518 |
| Gene: |
OTP |
More about : OTP |
| Long gene name: |
orthopedia homeobox |
| Synonyms gene name: |
orthopedia homolog (Drosophila) |
| Locus: |
5q14, 1 |
| Discovery year: |
1999-02-09 |
| Entrez gene record: |
23440 |
| Pubmed identfication: |
10458915 |
| Classification: |
PRD class homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000102171 |