| Long name: |
ALEXA FLUOR 488 Conjugated, OTP Polyclonal Antibody |
| Also known as: |
Anti-OTP PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
OTP |
| Specificity: |
This is a highly specific antibody against OTP |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OTP |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
At early embryonic stages in mice, Containing a homeobox DNA-binding domain and a OAR domain, OTP (orthopedia homeobox) is a 325 amino acid nuclear protein belonging to the paired homeobox family and Bicoid subfamily, OTP is expressed in neurons, OTP is highly conserved in evolution and is encoded by a gene located on human chromosome 5, OTP is suggested to be involved in the differentiation of hypothalamic neuroendocrine cells, anterior periventricular (aPV) and arcuate (ARN) nuclei, indicating a potential role for OTP as an upstream regulator of SIM2, supraoptic (SON), the expression of SIM2 is downregulated in the absence of OTP, which contains 181 million base pairs and comprises nearly 6% of the human genome, which give rise to the paraventricular (PVN), Homeodomain (HD) genes are helix-turn-helix transcription factors that play key roles in the specification of cell fates |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the OTP Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
OTP |
| Short name: |
OTP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, OTP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8518 |
| Gene: |
OTP |
More about : OTP |
| Long gene name: |
orthopedia homeobox |
| Synonyms gene name: |
orthopedia homolog (Drosophila) |
| Locus: |
5q14, 1 |
| Discovery year: |
1999-02-09 |
| Entrez gene record: |
23440 |
| Pubmed identfication: |
10458915 |
| Classification: |
PRD class homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000102171 |