| Long name: |
ALEXA FLUOR 647 Conjugated, MPP5/PALS1 Polyclonal Antibody |
| Also known as: |
Anti-MPP5/PALS1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MPP5/PALS1 |
| Specificity: |
This is a highly specific antibody against MPP5/PALS1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MPP5/PALS1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Because tumors exhibit perturbations in epithelial polarity, Loss of Pals1 function results in delayed polarization, Pals1, Pals1 presents a new potential target in the study of carcinogenesis, Tight junctions assist in the formation of polarity in the epithelia by establishing a barrier to separate apical and basolateral membranes, decreased transepithelial electrical resistance and an inability to form lumenal cysts, importantly, mediates interaction between the two complexes via interaction with Par6, the Crumbs-Pals1-Patj complex and the Cdc42-Par6-Par3-aPKC complex, Two highly conserved complexes are responsible for the assembly of tight junctions |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
PALS1 FLJ12615 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the MPP5/PALS1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
MPP5/PALS1 |
| Short name: |
MPP5/PALS1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, MPP5/PALS1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18669 |
| Gene: |
MPP5 |
More about : MPP5 |
| Long gene name: |
membrane palmitoylated protein 5 |
| Synonyms gene name: |
membrane protein, palmitoylated 5 , palmitoylated 5 (MAGUK p55 subfamily member 5) membrane protein |
| Synonyms name: |
stardust protein associated with Lin-7 1 |
| Locus: |
14q23, 3 |
| Discovery year: |
2002-05-23 |
| GenBank acession: |
AK022677 |
| Entrez gene record: |
64398 |
| Pubmed identfication: |
11927608 |
| RefSeq identity: |
NM_022474 |
| Classification: |
Crumbs complex Membrane associated guanylate kinases PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000171243 |