| Long name: |
Cy5, 5 Conjugated, GPR56 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GPR56 |
| Specificity: |
This is a highly specific antibody against GPR56 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human GPR56 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in the gene encoding for GPR56 can cause bilateral frontoparietal polymicrogyria (BFPP) which is characterized by disorganized cortical lamination, G-protein coupled receptor 56 (GPR56), G-protein coupled receptors mediate extracellular signals into intracellular signals (G-protein activation), GPR proteins are integral seven-pass membrane proteins with some conserved amino acid regions, GPR56 plays an important role in cell-cell interactions and is widely expressed, They respond to a great variety of signaling molecules, also designated TM7XN1 protein, also known as seven transmembrane receptors, are members of the largest protein family and play a role in many different stimulus-response pathways, contains one GPS domain, heart and thyroid gland, heptahelical receptors, including hormones, neurotransmitters and other proteins and peptides, or 7TM receptors, with highest levels detected in brain, G protein-coupled receptors (GPRs or GPCRs) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
TM7LN4 TM7XN1 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
GPR56 Conjugated |
| Short name: |
Conjugated, GPR56 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, G protein-coupled receptor 56 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BFPP and BPPR and TM7LN4 and TM7XN1, GPR56 and IDBG-33507 and ENSG00000205336 and 9289, Gpr56 and IDBG-183010 and ENSMUSG00000031785 and 14766, Plasma membranes, extracellular matrix binding, this GO :0001525 and angiogenesis and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007218 and neuropeptide signaling pathway and biological process this GO :0007266 and Rho protein signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007420 and brain development and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0010573 and vascular endothelial growth factor production and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0021801 and cerebral cortex radial glia guided migration and biological process this GO :0021819 and layer formation in cerebral cortex and biological process this GO :0035025 and positive regulation of Rho protein signal transduction and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0050840 and extracellular matrix binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070528 and protein kinase C signaling and biological process this GO :0097451 and glial limiting end-foot and cellular component this GO :2001223 and negative regulation of neuron migration and biological process, this GO :0004888 : transmembrane signaling receptor activity, this GO :0004888 : transmembrane signaling receptor activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0005518 : collagen binding and also this GO :0050840 : extracellular matrix binding, this GO :0004930 : G-protein coupled receptor activity, this GO :0005518 : collagen binding, this GO :0050840 : extracellular matrix binding, G protein-coupled receptor 56 |
| Identity: |
4512 |
| Gene: |
ADGRG1 |
More about : ADGRG1 |
| Long gene name: |
adhesion G protein-coupled receptor G1 |
| Synonyms gene: |
GPR56 |
| Synonyms gene name: |
G protein-coupled receptor 56 |
| Locus: |
16q21 |
| Discovery year: |
1998-10-12 |
| GenBank acession: |
AJ011001 |
| Entrez gene record: |
9289 |
| Pubmed identfication: |
10049584 10100861 25713288 |
| Classification: |
Adhesion G protein-coupled receptors, subfamily G |
| Havana BLAST/BLAT: |
OTTHUMG00000176742 |