| Long name: |
29) Monoclonal Antibody, 65, GPR56 (1443CT377 |
| Also known as: |
29) Monoclonal Antibody, 65, GPR56 (1443CT377 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GPR56 |
| Specificity: |
This is a highly specific antibody against GPR56 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
1443CT377, 29, 65 |
| Source: |
This antibody is generated from a mouse immunized with a recombinant protein |
| Gene ID number: |
9289 |
| Swiss Prot: |
Q9Y653 |
| Tested Applications: |
IF, WB |
| Recommended dilutions: |
WB(1:1000), IF(1:25) , WB(1:1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ADGRG1 N-terminal fragment: Plays a critical role in cancer progression by activating VEGFA production and angiogenesis through a signaling pathway mediated by PRKCA (PubMed:21724588), Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12 (PubMed:22238662), Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells, Plays a critical role in cancer progression by inhibiting VEGFA production threreby inhibiting angiogenesis through a signaling pathway mediated by PRKCA (PubMed:16757564, Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (By similarity), Plays an essential role in testis development (By similarity), PubMed:21724588), Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination (By similarity), Receptor involved in cell adhesion and probably in cell-cell interactions |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ADGRG1, Adhesion G-protein coupled receptor G1, BPPR, G-protein coupled receptor 56, GPR56, Protein TM7XN1, TM7LN4, TM7XN1, UNQ540/PRO1083, BFPP |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
29) Monoclonal, 65, GPR56 (1443CT377 |
| Short name: |
29) Monoclonal Antibody, 65, GPR56 (1443CT377 |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
29) monoclonal (Antibody to), 65, G protein-coupled receptor 56 (1443CT377 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BFPP and BPPR and TM7LN4 and TM7XN1, GPR56 and IDBG-33507 and ENSG00000205336 and 9289, Gpr56 and IDBG-183010 and ENSMUSG00000031785 and 14766, Plasma membranes, extracellular matrix binding, this GO :0001525 and angiogenesis and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007218 and neuropeptide signaling pathway and biological process this GO :0007266 and Rho protein signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007420 and brain development and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0010573 and vascular endothelial growth factor production and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0021801 and cerebral cortex radial glia guided migration and biological process this GO :0021819 and layer formation in cerebral cortex and biological process this GO :0035025 and positive regulation of Rho protein signal transduction and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0050840 and extracellular matrix binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070528 and protein kinase C signaling and biological process this GO :0097451 and glial limiting end-foot and cellular component this GO :2001223 and negative regulation of neuron migration and biological process, this GO :0004888 : transmembrane signaling receptor activity, this GO :0004888 : transmembrane signaling receptor activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0005518 : collagen binding and also this GO :0050840 : extracellular matrix binding, this GO :0004930 : G-protein coupled receptor activity, this GO :0005518 : collagen binding, this GO :0050840 : extracellular matrix binding, G protein-coupled receptor 56 |
| Identity: |
4512 |
| Gene: |
ADGRG1 |
More about : ADGRG1 |
| Long gene name: |
adhesion G protein-coupled receptor G1 |
| Synonyms gene: |
GPR56 |
| Synonyms gene name: |
G protein-coupled receptor 56 |
| Synonyms: |
TM7LN4 TM7XN1 |
| Locus: |
16q21 |
| Discovery year: |
1998-10-12 |
| GenBank acession: |
AJ011001 |
| Entrez gene record: |
9289 |
| Pubmed identfication: |
10049584 10100861 25713288 |
| Classification: |
Adhesion G protein-coupled receptors, subfamily G |
| Havana BLAST/BLAT: |
OTTHUMG00000176742 |