| Long name: |
Cy5 Conjugated, OPA1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
OPA1 |
| Specificity: |
This is a highly specific antibody against OPA1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
680-725/960 |
| Subcellular location: |
Mitochondrion |
| Source: |
KLH conjugated synthetic peptide derived from human OPA1 |
| Gene ID number: |
84692 |
| Swiss Prot: |
Q8NEL0 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in OPA1 are a cause of optic atrophy type 1, OPA1 is mostly expressed in retina but can also be expressed in brain, The OPA1 gene has been localized to 3q29, The gene is targeted to mitochondria and is involved in mitochondrial biogenesis, heart and skeletal muscle, testis, OPA1 is a 120kDa protein belonging to the dynamin family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
625, 650nm/670nm |
| Synonyms: |
NTG KIAA0567 FLJ12460 NPG MGM1 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
OPA1 Conjugated |
| Short name: |
Conjugated, OPA1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy5 |
| Alternative name: |
cyanine 5 coupled, optic atrophy 1 (autosomal dominant) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
GTP binding, OPA1 and IDBG-634327 and ENSBTAG00000019514 and 524142, OPA1 and IDBG-70072 and ENSG00000198836 and 4976, Opa1 and IDBG-151468 and ENSMUSG00000038084 and 74143, Plasma membranes, largeG and MGM1 and NPG and NTG, this GO :0000266 and mitochondrial fission and biological process this GO :0000287 and magnesium ion binding and molecular function this GO :0001843 and neural tube closure and biological process this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005758 and mitochondrial intermembrane space and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0007005 and mitochondrion organization and biological process this GO :0007007 and inner mitochondrial membrane organization and biological process this GO :0007601 and visual perception and biological process this GO :0008053 and mitochondrial fusion and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019896 and axon transport of mitochondrion and biological process this GO :0030061 and mitochondrial crista and cellular component this GO :0030425 and dendrite and cellular component this GO :0090201 and negative regulation of release of cytochrome c from mitochondria and biological process this GO :0090398 and cellular senescence and biological process this GO :2001243 and negative regulation of intrinsic apoptotic signaling pathway and biological process, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0003924 : GTPase activity and also this GO :0005515 : protein binding and also this GO :0005525 : GTP binding, this GO :0003924 : GTPase activity, this GO :0005515 : protein binding, this GO :0005525 : GTP binding, optic atrophy 1 (autosomal dominant) |
| Identity: |
8140 |
| Gene: |
OPA1 |
More about : OPA1 |
| Long gene name: |
OPA1, mitochondrial dynamin like GTPase |
| Synonyms gene name: |
optic atrophy 1 (autosomal dominant) |
| Synonyms name: |
mitochondrial , mitochondrial dynamin-like GTPase dynamin-like guanosine triphosphatase Dynamin-like 120 kDa protein |
| Locus: |
3q29 |
| Discovery year: |
1987-09-11 |
| GenBank acession: |
AB011139 |
| Entrez gene record: |
4976 |
| Pubmed identfication: |
9490303 |
| RefSeq identity: |
NM_130837 |
| Havana BLAST/BLAT: |
OTTHUMG00000149897 |
| Locus Specific Databases: |
Mutations of the Optic Atrophy 1 Gene LRG_337 |