| Long name: |
Cy3 Conjugated, DMPK Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DMPK |
| Specificity: |
This is a highly specific antibody against DMPK |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DMPK |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
DM arises through expansion of CTG repeats in the 3â, DMPK is implicated in myotonic muscular dystrophy (DM), L-type calcium channels, Mutant DMPK transcripts with an extended region of CUG repeats are retained in the nucleus (5), Other substrates for DMPK include myogenin, These transcripts also influence the expression of the DM locus-associated homeodomain protein (DMAHP)/SIX5, an autosomal dominant-inherited disorder that predominately affects skeletal and cardiac muscle and causes defects in cardiac conduction (2, and Phospholemman (PLM) (1), to mediate in part the DM phenotype (6), &euro, &trade, -UTR of the DMPK gene (4), 3), Myotonic dystrophy protein kinase is a multi-domain protein kinase found in muscle that is activated in response to G protein second messengers and proteolysis (1) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
DMK DM1PK MDPK MT-PK |
| Properties: |
1 of the DMPK Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DMPK Conjugated |
| Short name: |
Conjugated, DMPK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, DMPK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2933 |
| Gene: |
DMPK |
More about : DMPK |
| Long gene name: |
dystrophia myotonica protein kinase |
| Synonyms gene: |
DM1 DM |
| Synonyms gene name: |
dystrophia myotonica 1 (includes dystrophia myotonia protein kinase) |
| Synonyms name: |
dystrophia myotonica 1 DM protein kinase myotonin protein kinase A myotonic dystrophy associated protein kinase thymopoietin homolog |
| Locus: |
19q13, 32 |
| Discovery year: |
1997-10-10 |
| GenBank acession: |
L19268 |
| Entrez gene record: |
1760 |
| Pubmed identfication: |
1546325 1546326 |
| RefSeq identity: |
NM_004409 |
| Havana BLAST/BLAT: |
OTTHUMG00000182334 |