| Long name: |
DMPK Primary Polyclonal Antibody |
| Also known as: |
DMPK PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DMPK |
| Specificity: |
This is a highly specific antibody against DMPK |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DMPK |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
DM arises through expansion of CTG repeats in the 3â, DMPK is implicated in myotonic muscular dystrophy (DM), L-type calcium channels, Mutant DMPK transcripts with an extended region of CUG repeats are retained in the nucleus (5), Other substrates for DMPK include myogenin, These transcripts also influence the expression of the DM locus-associated homeodomain protein (DMAHP)/SIX5, an autosomal dominant-inherited disorder that predominately affects skeletal and cardiac muscle and causes defects in cardiac conduction (2, and Phospholemman (PLM) (1), to mediate in part the DM phenotype (6), &euro, &trade, -UTR of the DMPK gene (4), 3), Myotonic dystrophy protein kinase is a multi-domain protein kinase found in muscle that is activated in response to G protein second messengers and proteolysis (1) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DM, DM 1, DM kinase, DM protein kinase, DM-kinase, DM1, DM1 protein kinase, DM1PK, DMK, DMPK, DMPK_HUMAN, Dystrophia myotonica 1, Dystrophia myotonica protein kinase, MDPK, MT PK, MT-PK, Myotonic dystrophy associated protein kinase, Myotonic dystrophy protein kinase, Myotonin protein kinase, Myotonin protein kinase A, Myotonin-protein kinase, Thymopoietin homolog, Dystrophia myotonica protein kinase |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DMPK |
| Short name: |
DMPK Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DMPK (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2933 |
| Gene: |
DMPK |
More about : DMPK |
| Long gene name: |
dystrophia myotonica protein kinase |
| Synonyms gene: |
DM1 DM |
| Synonyms gene name: |
dystrophia myotonica 1 (includes dystrophia myotonia protein kinase) |
| Synonyms: |
DMK DM1PK MDPK MT-PK |
| Synonyms name: |
dystrophia myotonica 1 DM protein kinase myotonin protein kinase A myotonic dystrophy associated protein kinase thymopoietin homolog |
| Locus: |
19q13, 32 |
| Discovery year: |
1997-10-10 |
| GenBank acession: |
L19268 |
| Entrez gene record: |
1760 |
| Pubmed identfication: |
1546325 1546326 |
| RefSeq identity: |
NM_004409 |
| Havana BLAST/BLAT: |
OTTHUMG00000182334 |