| Long name: |
FITC Conjugated, EBF2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
EBF2 |
| Specificity: |
This is a highly specific antibody against EBF2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human EBF2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
EBF2 forms a homodimer or a heterodimer with a related family member, EBF2 is a transcription factor which, Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, Localized to the nucleus, OPG, OPG, activates the decoy receptor for RANKL, along with reduced bone mass and an increase in osteoclasts, in osteoblasts, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, in turn, regulates osteoclast differentiation, whose members are all helix-loop-helix transcription factors, Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
FLJ11500 COE2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
EBF2 Conjugated |
| Short name: |
FITC Conjugated, EBF2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, early B-cell factor 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0035563 and positive regulation of chromatin binding and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0046983 and protein dimerization activity and molecular function this GO :0050873 and brown fat cell differentiation and biological process this GO :0060612 and adipose tissue development and biological process, EBF2 and IDBG-281524 and ENSG00000221818 and 64641, Ebf2 and IDBG-175890 and ENSMUSG00000022053 and 13592, nuclei, protein dimerization activity, this GO :0001709 and cell fate determination and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0005515 : protein binding and also this GO :0046872 : metal ion binding and also this GO :0046983 : protein dimerization activity, this GO :0003682 : chromatin binding, this GO :0005515 : protein binding, this GO :0046872 : metal ion binding, this GO :0046983 : protein dimerization activity, 59602 and IDBG-635598 and ENSBTAG00000040390 and, early B-cell factor 2 |
| Identity: |
19090 |
| Gene: |
EBF2 |
More about : EBF2 |
| Long gene name: |
early B-cell factor 2 |
| Locus: |
8p21, 2 |
| Discovery year: |
2002-08-09 |
| GenBank acession: |
AK021562 AK001144 |
| Entrez gene record: |
64641 |
| Pubmed identfication: |
9151732 |
| RefSeq identity: |
NM_022659 |
| Havana BLAST/BLAT: |
OTTHUMG00000163838 |