| Long name: |
EBF2 Primary Polyclonal Antibody |
| Also known as: |
EBF2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
EBF2 |
| Specificity: |
This is a highly specific antibody against EBF2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EBF2 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
EBF2 forms a homodimer or a heterodimer with a related family member, EBF2 is a transcription factor which, Lack of EBF2 has been found to cause a small defect in the terminal differentiation of osteoblasts, Localized to the nucleus, OPG, OPG, activates the decoy receptor for RANKL, along with reduced bone mass and an increase in osteoclasts, in osteoblasts, in synergy with the Wnt-responsive LEF1/CTNNB1 pathway, in turn, regulates osteoclast differentiation, whose members are all helix-loop-helix transcription factors, Early B-cell factor 2 is a 575 amino acid protein belonging to the COE family of proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
COE2, COE2_HUMAN, Collier Olf and EBF 2, EBF 2, Early B cell factor 2, FLJ11500, Metencephalon mesencephalnon olfactory transcription factor 1, O/E 3, O/E3, OE 3, OE3, OLF 1/EBF like 3, Transcription factor COE2, COE 2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
EBF2 |
| Short name: |
EBF2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
early B-cell factor 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0035563 and positive regulation of chromatin binding and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0046983 and protein dimerization activity and molecular function this GO :0050873 and brown fat cell differentiation and biological process this GO :0060612 and adipose tissue development and biological process, EBF2 and IDBG-281524 and ENSG00000221818 and 64641, Ebf2 and IDBG-175890 and ENSMUSG00000022053 and 13592, nuclei, protein dimerization activity, this GO :0001709 and cell fate determination and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0005515 : protein binding and also this GO :0046872 : metal ion binding and also this GO :0046983 : protein dimerization activity, this GO :0003682 : chromatin binding, this GO :0005515 : protein binding, this GO :0046872 : metal ion binding, this GO :0046983 : protein dimerization activity, 59602 and IDBG-635598 and ENSBTAG00000040390 and, early B-cell factor 2 |
| Identity: |
19090 |
| Gene: |
EBF2 |
More about : EBF2 |
| Long gene name: |
early B-cell factor 2 |
| Synonyms: |
FLJ11500 COE2 |
| Locus: |
8p21, 2 |
| Discovery year: |
2002-08-09 |
| GenBank acession: |
AK021562 AK001144 |
| Entrez gene record: |
64641 |
| Pubmed identfication: |
9151732 |
| RefSeq identity: |
NM_022659 |
| Havana BLAST/BLAT: |
OTTHUMG00000163838 |