| Long name: |
FITC Conjugated, NDUFS7 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NDUFS7 |
| Specificity: |
This is a highly specific antibody against NDUFS7 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human NDUFS7 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
As a subunit of mitochondrial complex I, By oxidizing NADH that is produced in the Krebs cycle, Defects in the gene encoding NDUFS7 are the cause of Leigh syndrome, Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any of the subunits can lead to various myopathies and neuropathies, NDUFS7 (NADH dehydrogenase [ubiquinone] iron-sulfur protein 7), a severe neurological disorder that is characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions, also designated NADH-ubiquinone oxidoreductase 20 kDa subunit, is a 213 amino acid protein that is suggested to be required for catalytic activity, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, Located in the mitochondrial inner membrane |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
PSST FLJ46880 FLJ45860 CI-20 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NDUFS7 Conjugated |
| Short name: |
FITC Conjugated, NDUFS7 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, NDUFS7 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7714 |
| Gene: |
NDUFS7 |
More about : NDUFS7 |
| Long gene name: |
NADH:ubiquinone oxidoreductase core subunit S7 |
| Synonyms gene name: |
20kDa (NADH-coenzyme Q reductase) , NADH dehydrogenase (ubiquinone) Fe-S protein 7 (20kD) (NADH-coenzyme Q reductase) NADH dehydrogenase (ubiquinone) Fe-S protein 7 |
| Synonyms name: |
complex I 20kDa subunit NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial |
| Locus: |
19p13, 3 |
| Discovery year: |
1996-07-26 |
| GenBank acession: |
AF115969 |
| Entrez gene record: |
374291 |
| Pubmed identfication: |
8938450 |
| RefSeq identity: |
NM_024407 |
| Classification: |
NADH:ubiquinone oxidoreductase core subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000168077 |