| Long name: |
ALEXA FLUOR 488 Conjugated, NDUFS7 Polyclonal Antibody |
| Also known as: |
Anti-NDUFS7 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NDUFS7 |
| Specificity: |
This is a highly specific antibody against NDUFS7 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NDUFS7 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
As a subunit of mitochondrial complex I, By oxidizing NADH that is produced in the Krebs cycle, Defects in the gene encoding NDUFS7 are the cause of Leigh syndrome, Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any of the subunits can lead to various myopathies and neuropathies, NDUFS7 (NADH dehydrogenase [ubiquinone] iron-sulfur protein 7), a severe neurological disorder that is characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions, also designated NADH-ubiquinone oxidoreductase 20 kDa subunit, is a 213 amino acid protein that is suggested to be required for catalytic activity, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, Located in the mitochondrial inner membrane |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
PSST FLJ46880 FLJ45860 CI-20 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the NDUFS7 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
NDUFS7 |
| Short name: |
NDUFS7 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, NDUFS7 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7714 |
| Gene: |
NDUFS7 |
More about : NDUFS7 |
| Long gene name: |
NADH:ubiquinone oxidoreductase core subunit S7 |
| Synonyms gene name: |
20kDa (NADH-coenzyme Q reductase) , NADH dehydrogenase (ubiquinone) Fe-S protein 7 (20kD) (NADH-coenzyme Q reductase) NADH dehydrogenase (ubiquinone) Fe-S protein 7 |
| Synonyms name: |
complex I 20kDa subunit NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial |
| Locus: |
19p13, 3 |
| Discovery year: |
1996-07-26 |
| GenBank acession: |
AF115969 |
| Entrez gene record: |
374291 |
| Pubmed identfication: |
8938450 |
| RefSeq identity: |
NM_024407 |
| Classification: |
NADH:ubiquinone oxidoreductase core subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000168077 |