| Long name: |
ALEXA FLUOR 647 Conjugated, MTMR2 Polyclonal Antibody |
| Also known as: |
Anti-MTMR2 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MTMR2 |
| Specificity: |
This is a highly specific antibody against MTMR2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MTMR2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
MTMR family members hydrolyze both Phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3, MTMR2 interacts with MTMR5, MTMR3 and MTMR4 can either interact with each other or self associate, MTMR6 regulates the activity of the calcium-activated potassium channel 3, MTMR9 regulates the activity of MTMR7 and MTMR8, Mutations in MTMR2 cause autosomal recessive Charcot-Marie-Tooth type 4B1 (CMT4B1), They are protein tyrosine phosphatases that utilize inositol phospholipids, an inactive family member that increases the enzymatic activity of MTMR2 and dictates its subcellular localization, as substrates, focally folded myelin sheaths and demyelination, rather than phosphoproteins, which is characterized by reduced nerve conduction velocities, 1, 5)P2, Myotubularin and the myotubularin-related proteins (MTMR1-9) belong to a highly conserved family of eukaryotic phosphatases |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
KIAA1073 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the MTMR2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
MTMR2 |
| Short name: |
MTMR2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, MTMR2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7450 |
| Gene: |
MTMR2 |
More about : MTMR2 |
| Long gene name: |
myotubularin related protein 2 |
| Synonyms gene: |
CMT4B |
| Synonyms name: |
phosphatidylinositol-3-phosphatase phosphoinositide-3-phosphatase |
| Locus: |
11q21 |
| Discovery year: |
1999-02-05 |
| GenBank acession: |
U58033 |
| Entrez gene record: |
8898 |
| Pubmed identfication: |
8640223 9736772 |
| RefSeq identity: |
NM_016156 |
| Classification: |
Phosphoinositide phosphatases Myotubularins |
| Havana BLAST/BLAT: |
OTTHUMG00000153837 |
| Locus Specific Databases: |
Inherited Peripheral Neuropathies Mutation Database LRG_257 |