| Catalog number: | bs-11732R-A555 |
|---|---|
| Price: | 671 € |
| Supplier: | abebio |
| Product name: | Doppel/DPL Antibody, ALEXA FLUOR 555 |
| Quantity: | 1x plate of 96 wells |
| Related search: |
| Long name: | ALEXA FLUOR 555 Conjugated, Doppel/DPL Polyclonal Antibody |
|---|---|
| Also known as: | Anti-Doppel/DPL PAb ALEXA FLUOR 555 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 555, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | Doppel/DPL |
| Specificity: | This is a highly specific antibody against Doppel/DPL |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Doppel |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | BSE in cattle, Dpl does not appear to contribute to prion disease progression, Dpl is also thought to play a role in angiogenesis, Dpl is characterized by an alpha-helical conformation, Dpl is highly expressed in adult testis and heart and is detectable in the brain of neonatal mice, Infectious PrPSc is highly expressed in the brain of animals affected by TSEs, The PRND gene locus, and Cruetzfeldt-Jacob disease in humans, and it is presented on the cell surface by a glycosylphosphatidylinositol anchor, and two N-linked oligosaccharides, but ectopic expression of Dpl is implicated in neuronal degeneration of ataxic PRP-deficient mice, encodes for the doppel protein (Dpl), including scrapie in sheep, infectious or sporadic, intramolecular disulfide bonds, lethal neurodegenerative disorders involving alterations of the prion protein (PrP), located on human chromosome 20p, specifically maturation of the blood-brain barrier, which exhibits approximately 25% sequence homology with PrP, Prion diseases or transmissible spongiform encephalopathies (TSEs) are manifested as genetic |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 553nm/568nm |
| Synonyms: | DPL dJ1068H6, 4 DOPPEL PrPLP |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 555, Alexa Fluor |
| Gene target: | Doppel/DPL |
| Short name: | Doppel/DPL Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 555 |
| Alternative name: | ALEXA FLUOR 555, Doppel/DPL (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 15748 |
| Gene: | PRND | More about : PRND |
| Long gene name: | prion like protein doppel |
| Synonyms gene name: | prion protein 2 (dublet) |
| Synonyms name: | prion-like protein doppel downstream prion protein-like gene |
| Locus: | 20p13 |
| Discovery year: | 2001-05-30 |
| GenBank acession: | AF106918 |
| Entrez gene record: | 23627 |
| Pubmed identfication: | 10525406 10577243 |
| RefSeq identity: | NM_012409 |
| Havana BLAST/BLAT: | OTTHUMG00000031789 |
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