| Long name: |
FITC Conjugated, HIPPI Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HIPPI |
| Specificity: |
This is a highly specific antibody against HIPPI |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human HIPPI |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Huntingtonâ, Polyglutamine expansion reduces the level of association between Hip-1 and Htt, The Hippi-Hip-1 heterodimer is a pro-apoptotic complex that recruits procaspase-8 and initiates caspase-8 activation, The human hippi gene maps to chromosome 3q13, thereby increasing levels of free Hip-1 that then can be the candidate protein Hippi (Hip-1 protein interactor), which may contribute to the neuronal cell death observed in individuals diagnosed with Huntingtonâ, which occur later in human life, &euro, &euro, &trade, &trade, 13 and encodes a 429 amino acid protein, Programmed neuronal cell death is a feature of neurodegenerative disorders such as Alzheimer's and Huntington's disease, s disease, s disease at the molecular and cell level is characterized by polyglutamine expansion of the protein huntingtin (Htt) that leads to apoptotis-mediated neurodegenerative loss of medium spiny neurons throughout the striatum |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
FLJ10147 HIPPI MHS4R2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HIPPI Conjugated |
| Short name: |
FITC Conjugated, HIPPI Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, HIPPI (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17367 |
| Gene: |
IFT57 |
More about : IFT57 |
| Long gene name: |
intraflagellar transport 57 |
| Synonyms gene: |
ESRRBL1 |
| Synonyms gene name: |
estrogen-related receptor beta like 1 intraflagellar transport 57 homolog (Chlamydomonas) |
| Locus: |
3q13, 12-q13, 13 |
| Discovery year: |
2002-01-18 |
| GenBank acession: |
AK001009 |
| Entrez gene record: |
55081 |
| RefSeq identity: |
NM_018010 |
| Classification: |
Intraflagellar transport proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000159223 |