| Long name: |
HIPPI Primary Polyclonal Antibody |
| Also known as: |
HIPPI PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
HIPPI |
| Specificity: |
This is a highly specific antibody against HIPPI |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HIPPI |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Huntingtonâ, Polyglutamine expansion reduces the level of association between Hip-1 and Htt, The Hippi-Hip-1 heterodimer is a pro-apoptotic complex that recruits procaspase-8 and initiates caspase-8 activation, The human hippi gene maps to chromosome 3q13, thereby increasing levels of free Hip-1 that then can be the candidate protein Hippi (Hip-1 protein interactor), which may contribute to the neuronal cell death observed in individuals diagnosed with Huntingtonâ, which occur later in human life, &euro, &euro, &trade, &trade, 13 and encodes a 429 amino acid protein, Programmed neuronal cell death is a feature of neurodegenerative disorders such as Alzheimer's and Huntington's disease, s disease, s disease at the molecular and cell level is characterized by polyglutamine expansion of the protein huntingtin (Htt) that leads to apoptotis-mediated neurodegenerative loss of medium spiny neurons throughout the striatum |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CDNA FLJ10147 fis clone HEMBA1003369, DERP 8, DERP8, Dermal papilla-derived protein 8, ESRRBL1 protein, Esrrbl 1, Esrrbl1, Estrogen related receptor beta like 1, Estrogen related receptor beta like protein 1, Estrogen-related receptor beta like 1, Estrogen-related receptor beta-like protein 1, FLJ10147, HIP1 interacting protein HIPPI, HIP1-interacting protein, HIPPI, Hip1 Interacting Protein, Hip1 protein interactor, Huntingtin interacting protein 1 interacting protein, Huntingtin interacting protein 1 protein interactor, Huntingtin-interacting protein-1 protein interactor, Intraflagellar transport 57 homolog, Intraflagellar transport 57 homolog Chlamydomonas, Intraflagellar transport protein 57 homolog, MHS4R2, T 57, T57_HUMAN, Vestrogen related receptor beta like 1, Vestrogen-related receptor beta like 1, t57, Dermal papilla derived protein 8 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HIPPI |
| Short name: |
HIPPI Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HIPPI (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17367 |
| Gene: |
IFT57 |
More about : IFT57 |
| Long gene name: |
intraflagellar transport 57 |
| Synonyms gene: |
ESRRBL1 |
| Synonyms gene name: |
estrogen-related receptor beta like 1 intraflagellar transport 57 homolog (Chlamydomonas) |
| Synonyms: |
FLJ10147 HIPPI MHS4R2 |
| Locus: |
3q13, 12-q13, 13 |
| Discovery year: |
2002-01-18 |
| GenBank acession: |
AK001009 |
| Entrez gene record: |
55081 |
| RefSeq identity: |
NM_018010 |
| Classification: |
Intraflagellar transport proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000159223 |