| Long name: |
ALEXA FLUOR 647 Conjugated, HIPPI Polyclonal Antibody |
| Also known as: |
Anti-HIPPI PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HIPPI |
| Specificity: |
This is a highly specific antibody against HIPPI |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HIPPI |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Huntingtonâ, Polyglutamine expansion reduces the level of association between Hip-1 and Htt, The Hippi-Hip-1 heterodimer is a pro-apoptotic complex that recruits procaspase-8 and initiates caspase-8 activation, The human hippi gene maps to chromosome 3q13, thereby increasing levels of free Hip-1 that then can be the candidate protein Hippi (Hip-1 protein interactor), which may contribute to the neuronal cell death observed in individuals diagnosed with Huntingtonâ, which occur later in human life, &euro, &euro, &trade, &trade, 13 and encodes a 429 amino acid protein, Programmed neuronal cell death is a feature of neurodegenerative disorders such as Alzheimer's and Huntington's disease, s disease, s disease at the molecular and cell level is characterized by polyglutamine expansion of the protein huntingtin (Htt) that leads to apoptotis-mediated neurodegenerative loss of medium spiny neurons throughout the striatum |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
FLJ10147 HIPPI MHS4R2 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the HIPPI Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
HIPPI |
| Short name: |
HIPPI Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, HIPPI (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17367 |
| Gene: |
IFT57 |
More about : IFT57 |
| Long gene name: |
intraflagellar transport 57 |
| Synonyms gene: |
ESRRBL1 |
| Synonyms gene name: |
estrogen-related receptor beta like 1 intraflagellar transport 57 homolog (Chlamydomonas) |
| Locus: |
3q13, 12-q13, 13 |
| Discovery year: |
2002-01-18 |
| GenBank acession: |
AK001009 |
| Entrez gene record: |
55081 |
| RefSeq identity: |
NM_018010 |
| Classification: |
Intraflagellar transport proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000159223 |