| Long name: |
Cy3 Conjugated, FIG4/SAC3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FIG4/SAC3 |
| Specificity: |
This is a highly specific antibody against FIG4/SAC3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human FIG4 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ALS11 is characterized by the degeneration of upper motor neurons in the brain and lower neurons in the spinal cord, CMT4J is a recessive demyelinating disorder of the peripheral nervous system and is characterized by reduced motor nerve conduction velocities and axonal degeneration, Defects in the gene encoding FIG4 are the cause of Charcot-Marie-Tooth disease type 4J (CMT4J) and amyotrophic lateral sclerosis type 11 (ALS11), Unlike CMT4J, both of which negatively affect the nervous system, causing paralysis and, death, ultimately, FIG4 is a 907 amino acid protein that contains one SAC domain through which it is thought to function as a phosphoinositide phosphatase that may play an important role in signal transduction and vesicle trafficking |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
SAC3 hSac3 dJ249I4, 1 ALS11 CMT4J |
| Properties: |
1 of the FIG4/SAC3 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FIG4/SAC3 Conjugated |
| Short name: |
Conjugated, FIG4/SAC3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, FIG4/SAC3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16873 |
| Gene: |
FIG4 |
More about : FIG4 |
| Long gene name: |
FIG4 phosphoinositide 5-phosphatase |
| Synonyms gene: |
KIAA0274 |
| Synonyms gene name: |
KIAA0274 FIG4 homolog (S, SAC1 lipid phosphatase domain containing (S, cerevisiae) , cerevisiae) FIG4 homolog |
| Locus: |
6q21 |
| Discovery year: |
2003-11-26 |
| GenBank acession: |
D87464 |
| Entrez gene record: |
9896 |
| Pubmed identfication: |
9039502 11274189 17572665 |
| RefSeq identity: |
NM_014845 |
| Classification: |
Phosphoinositide phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000015352 |
| Locus Specific Databases: |
LRG_241 |