| Long name: |
ALEXA FLUOR 488 Conjugated, FIG4/SAC3 Polyclonal Antibody |
| Also known as: |
Anti-FIG4/SAC3 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FIG4/SAC3 |
| Specificity: |
This is a highly specific antibody against FIG4/SAC3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FIG4 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
ALS11 is characterized by the degeneration of upper motor neurons in the brain and lower neurons in the spinal cord, CMT4J is a recessive demyelinating disorder of the peripheral nervous system and is characterized by reduced motor nerve conduction velocities and axonal degeneration, Defects in the gene encoding FIG4 are the cause of Charcot-Marie-Tooth disease type 4J (CMT4J) and amyotrophic lateral sclerosis type 11 (ALS11), Unlike CMT4J, both of which negatively affect the nervous system, causing paralysis and, death, ultimately, FIG4 is a 907 amino acid protein that contains one SAC domain through which it is thought to function as a phosphoinositide phosphatase that may play an important role in signal transduction and vesicle trafficking |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
SAC3 hSac3 dJ249I4, 1 ALS11 CMT4J |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the FIG4/SAC3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
FIG4/SAC3 |
| Short name: |
FIG4/SAC3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, FIG4/SAC3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16873 |
| Gene: |
FIG4 |
More about : FIG4 |
| Long gene name: |
FIG4 phosphoinositide 5-phosphatase |
| Synonyms gene: |
KIAA0274 |
| Synonyms gene name: |
KIAA0274 FIG4 homolog (S, SAC1 lipid phosphatase domain containing (S, cerevisiae) , cerevisiae) FIG4 homolog |
| Locus: |
6q21 |
| Discovery year: |
2003-11-26 |
| GenBank acession: |
D87464 |
| Entrez gene record: |
9896 |
| Pubmed identfication: |
9039502 11274189 17572665 |
| RefSeq identity: |
NM_014845 |
| Classification: |
Phosphoinositide phosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000015352 |
| Locus Specific Databases: |
LRG_241 |