| Long name: |
ALEXA FLUOR 647 Conjugated, UCHL3 Polyclonal Antibody |
| Also known as: |
Anti-UCHL3 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
UCHL3 |
| Specificity: |
This is a highly specific antibody against UCHL3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
130-180/230 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UCHL3 |
| Gene ID Number: |
7347 |
| Swiss Prot: |
P15374 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Examination of specific brain regions reveals expression in all areas tested, Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors, Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease, The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1, The gene which encodes UCH-L1 maps to human chromosome 4p14, UCH-L1 is expressed in brain neurons, UCH-L1 represents 1 to 2% of total soluble brain protein, UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin, particularly in the substantia nigra, UCH-L1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the UCHL3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
UCHL3 |
| Short name: |
UCHL3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, UCHL3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12515 |
| Gene: |
UCHL3 |
More about : UCHL3 |
| Long gene name: |
ubiquitin C-terminal hydrolase L3 |
| Synonyms gene name: |
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) |
| Synonyms name: |
ubiquitin thiolesterase |
| Locus: |
13q22, 2 |
| Discovery year: |
1991-07-15 |
| GenBank acession: |
M30496 |
| Entrez gene record: |
7347 |
| Pubmed identfication: |
2530630 |
| RefSeq identity: |
NM_006002 |
| Classification: |
Ubiquitin C-terminal hydrolases |
| Havana BLAST/BLAT: |
OTTHUMG00000017090 |