| Long name: |
UCHL3 (AF9G8) Monoclonal Antibody |
| Also known as: |
UCHL3 (AF9G8) Monoclonal Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
UCHL3 |
| Specificity: |
This is a highly specific antibody against UCHL3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Monoclonal |
| Clone number: |
AF9G8 |
| Concentration: |
1ug per 1ul |
| Source: |
Recombinant human protein purified from E, coli (GST-UCHL3) |
| Gene ID number: |
7347 |
| Swiss Prot: |
P15374 |
| Tested Applications: |
WB |
| Recommended dilutions: |
5ug/mL), WB (0 |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis, Can hydrolyze UBB(+1), Deubiquitinates ENAC in apical compartments, Has a 10-fold preference for Arg and Lys at position P3", Indirectly increases the phosphorylation of IGFIR, May be involved in working memory, Required for stress-response retinal, Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8, a mutated form of ubiquitin which is not effectively degraded by the proteasome and is associated with neurogenerative disorders, and exhibits a preference towards 'Lys-48'-linked Ubiquitin chains, skeletal muscle and germ cell maintenance, thereby regulating apical membrane recycling, Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins |
| Purification method: |
Purified by Protein G |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
UCHL3, Ubiquitin carboxyl-terminal hydrolase isozyme L3, Ubiquitin thioesterase L3, UCH-L3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target: |
UCHL3 (AF9G8) Monoclonal |
| Short name: |
UCHL3 (AF9G8) Monoclonal Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
UCHL3 (AF9G8) monoclonal (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12515 |
| Gene: |
UCHL3 |
More about : UCHL3 |
| Long gene name: |
ubiquitin C-terminal hydrolase L3 |
| Synonyms gene name: |
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) |
| Synonyms name: |
ubiquitin thiolesterase |
| Locus: |
13q22, 2 |
| Discovery year: |
1991-07-15 |
| GenBank acession: |
M30496 |
| Entrez gene record: |
7347 |
| Pubmed identfication: |
2530630 |
| RefSeq identity: |
NM_006002 |
| Classification: |
Ubiquitin C-terminal hydrolases |
| Havana BLAST/BLAT: |
OTTHUMG00000017090 |