| Long name: |
FITC Conjugated, NOMO1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NOMO1 |
| Specificity: |
This is a highly specific antibody against NOMO1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human NOMO1 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
All three NOMO proteins share similar functions and have been difficult to characterize individually, NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), NOMO1 (Nodal modulator 1), NOMO2 and NOMO3, a heritable disorder of connective tissue, also known as PM5, and are rapidly degraded or stabilized by Nicalin, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6), is a 1, 222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa, Three highly similar proteins termed NOMO1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
PM5 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NOMO1 Conjugated |
| Short name: |
FITC Conjugated, NOMO1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, NOMO1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30060 |
| Gene: |
NOMO1 |
More about : NOMO1 |
| Long gene name: |
NODAL modulator 1 |
| Locus: |
16p13, 11 |
| Discovery year: |
2004-09-10 |
| GenBank acession: |
X57398 |
| Entrez gene record: |
23420 |
| Pubmed identfication: |
1310294 15257293 |
| Havana BLAST/BLAT: |
OTTHUMG00000090541 |