| Long name: |
Biotin Conjugated, NOMO1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NOMO1 |
| Specificity: |
This is a highly specific antibody against NOMO1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human NOMO1 |
| Tested applications: |
IHC-P |
| Recommended dilutions: |
IHC-P(1:100-500) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
All three NOMO proteins share similar functions and have been difficult to characterize individually, NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), NOMO1 (Nodal modulator 1), NOMO2 and NOMO3, a heritable disorder of connective tissue, also known as PM5, and are rapidly degraded or stabilized by Nicalin, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6), is a 1, 222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa, Three highly similar proteins termed NOMO1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
PM5 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NOMO1 Conjugated |
| Short name: |
Conjugated, NOMO1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, NOMO1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30060 |
| Gene: |
NOMO1 |
More about : NOMO1 |
| Long gene name: |
NODAL modulator 1 |
| Locus: |
16p13, 11 |
| Discovery year: |
2004-09-10 |
| GenBank acession: |
X57398 |
| Entrez gene record: |
23420 |
| Pubmed identfication: |
1310294 15257293 |
| Havana BLAST/BLAT: |
OTTHUMG00000090541 |