| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NOMO1 |
| Specificity: |
This antibody reacts specifically with NOMO1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NOMO1 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
All three NOMO proteins share similar functions and have been difficult to characterize individually, NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), NOMO1 (Nodal modulator 1), NOMO2 and NOMO3, a heritable disorder of connective tissue, also known as PM5, and are rapidly degraded or stabilized by Nicalin, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6), is a 1, 222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa, Three highly similar proteins termed NOMO1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PM5 |
| Also known as: |
NOMO1 Polyclonal Antibody |
| Other name: |
Anti-NOMO1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NOMO1 |
| Short name: |
Anti-NOMO1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NOMO1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
30060 |
| Gene: |
NOMO1 |
More about : NOMO1 |
| Long gene name: |
NODAL modulator 1 |
| Locus: |
16p13, 11 |
| Discovery year: |
2004-09-10 |
| GenBank acession: |
X57398 |
| Entrez gene record: |
23420 |
| Pubmed identfication: |
1310294 15257293 |
| Havana BLAST/BLAT: |
OTTHUMG00000090541 |