Gemin 2/SMA Antibody, ALEXA FLUOR 555

Catalog number:	bs-11562R-A555 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	Gemin 2/SMA Antibody, ALEXA FLUOR 555
Quantity:	0.1ml
Related search:	gemin sma alexa smn gene fluor spinal human synonyms disease survival

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Long name:	ALEXA FLUOR 555 Conjugated, Gemin 2/SMA Polyclonal Antibody
Also known as:	Anti-Gemin 2/SMA PAb ALEXA FLUOR 555
Category:	Conjugated Primary Antibodies
Conjugated with:	555, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Gemin 2/SMA
Specificity:	This is a highly specific antibody against Gemin 2/SMA
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Gemin 2
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Gemin2 (formerly known as SIP1 for SMN interacting protein) associates directly with SMN and is a part of the SMN complex containing Gemin3 (a DEAD-box RNA helicase), Gemin2 is expressed in spinal cord, Gemin4, Gemin5 and Gemin6, It can be induced by TGFâ, It is found in both the cytoplasm and the nucleus, SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene, SMN is expressed in a wide variety of tissues including brain, The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus, The SMN-Gemin2 complex is associated with spliceosomal snRNAs U1 and U5, The gene encoding Gemin2 maps to human chromosome 14q13, The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies), and moderately in skeletal and cardiac muscle, as well as several spliceosomal snRNP proteins, kidney, liver and spinal cord, treatment and expression is high in several E-cadherin negative human carcinoma cell lines, &circ, «, Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	553nm/568nm
Synonyms:	BCD541 SMNT SMA1 SMA2 SMA3 GEMIN1 TDRD16A
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	ALEXA FLUOR 555, Alexa Fluor
Gene target:	Gemin 2/SMA
Short name:	Gemin 2/SMA Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 555
Alternative name:	ALEXA FLUOR 555, Gemin 2/SMA (Antibody to)
Alternative technique:	antibodies
Identity:	11117
Gene:	SMN1 | More about : SMN1
Long gene name:	survival of motor neuron 1, telomeric
Synonyms gene:	SMA@ SMA
Synonyms gene name:	Kugelberg-Welander disease) , spinal muscular atrophy (Werdnig-Hoffmann disease
Synonyms name:	gemin-1 tudor domain containing 16A
Locus:	5q13, 2
Discovery year:	1996-12-12
GenBank acession:	U18423
Entrez gene record:	6606
Pubmed identfication:	7813012
RefSeq identity:	NM_000344
Classification:	Tudor domain containing
Havana BLAST/BLAT:	OTTHUMG00000099361
Locus Specific Databases:	SMN1 - Spinal Muscular Atrophy (SMA) Leiden Muscular Dystrophy pages ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_676

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