| Long name: |
ALEXA FLUOR 350 Conjugated, EN2/Engrailed 2 Polyclonal Antibody |
| Also known as: |
Anti-EN2/Engrailed 2 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
EN2/Engrailed 2 |
| Specificity: |
This is a highly specific antibody against EN2/Engrailed 2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
300-333/333 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EN2/Engrailed 2 |
| Gene ID Number: |
2020 |
| Swiss Prot: |
P19622 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Different mutations in the mouse homologs, During early brain development mouse EN-2 is expressed in a broad band across most of the mid-hindbrain region, EN-1 and EN-2, EN-1 and EN-2 regulate expression of a-synuclein, EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum, EN-2 is also expressed in mouse myoblasts and has been assiciated with cerebellar hypoplasia, EN2, Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system, In Drosophila, a gene that is genetically linked to Parkinsonâ, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation, produce different developmental defects that frequently are lethal, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments, &euro, &trade, The engrailed-2 gene, s disease |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
EN2/Engrailed 2 |
| Short name: |
EN2/Engrailed 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, EN2/Engrailed 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3343 |
| Gene: |
EN2 |
More about : EN2 |
| Long gene name: |
engrailed homeobox 2 |
| Locus: |
7q36, 3 |
| Discovery year: |
1988-08-31 |
| Entrez gene record: |
2020 |
| RefSeq identity: |
NM_001427 |
| Classification: |
NKL subclass homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000151354 |