| Long name: |
FITC Conjugated, BBS8/TTC8 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
BBS8/TTC8 |
| Specificity: |
This is a highly specific antibody against BBS8/TTC8 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human BBS8 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
BBS is a heterogeneous disorder mapping to eight genetic loci and encoding eight proteins, BBS patients also have an increased risk of developing diabetes, BBS1-BBS8, BBS2 contains two overlapping genes: BBS2L1 and BBS2L2, BBS7 contains 672 amino acids and is expressed at low to moderate levels in most human tissues, BBSL1 was re-named BBS7, Five BBS proteins encode basal body or cilia proteins, and congenital heart defects, and developmental delay, hypertension, hypogenitalism, photoreceptor degeneration, polydactyly, renal abnormalities, suggesting that BBS is a ciliary dysfunction disorder, whereas BBS2L2 independently funcitons as BBS1, Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
BBS8 RP51 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
BBS8/TTC8 Conjugated |
| Short name: |
FITC Conjugated, BBS8/TTC8 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, BBS8/tetratricopeptide repeat domain 8 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cytoplasm, TTC8 and IDBG-15274 and ENSG00000165533 and 123016, TTC8 and IDBG-646921 and ENSBTAG00000030432 and 615652, Ttc8 and IDBG-163183 and ENSMUSG00000021013 and 76260, protein binding, this GO :0001103 and RNA polymerase II repressing transcription factor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005929 and cilium and cellular component this GO :0007411 and axon guidance and biological process this GO :0007608 and sensory perception of smell and biological process this GO :0015031 and protein transport and biological process this GO :0021772 and olfactory bulb development and biological process this GO :0032391 and photoreceptor connecting cilium and cellular component this GO :0032880 and regulation of protein localization and biological process this GO :0034464 and BBSome and cellular component this GO :0035058 and nonmotile primary cilium assembly and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0036064 and ciliary basal body and cellular component this GO :0042384 and cilium assembly and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0048560 and establishment of anatomical structure orientation and biological process this GO :0050893 and sensory processing and biological process this GO :0060170 and ciliary membrane and cellular component this GO :0060219 and camera-type eye photoreceptor cell differentiation and biological process this GO :0061326 and renal tubule development and biological process, this GO :0001103 : RNA polymerase II repressing transcription factor binding, this GO :0001103 : RNA polymerase II repressing transcription factor binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, tetratricopeptide repeat domain 8 |
| Identity: |
20087 |
| Gene: |
TTC8 |
More about : TTC8 |
| Long gene name: |
tetratricopeptide repeat domain 8 |
| Locus: |
14q31, 3 |
| Discovery year: |
2002-12-17 |
| GenBank acession: |
AK093891 |
| Entrez gene record: |
123016 |
| Pubmed identfication: |
14520415 20451172 |
| RefSeq identity: |
NM_144596 |
| Classification: |
Bardet-Biedl syndrome associated Tetratricopeptide repeat domain containing BBSome |
| Havana BLAST/BLAT: |
OTTHUMG00000170884 |