| Long name: |
Cy5 Conjugated, BBS8/TTC8 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
BBS8/TTC8 |
| Specificity: |
This is a highly specific antibody against BBS8/TTC8 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human BBS8 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
BBS is a heterogeneous disorder mapping to eight genetic loci and encoding eight proteins, BBS patients also have an increased risk of developing diabetes, BBS1-BBS8, BBS2 contains two overlapping genes: BBS2L1 and BBS2L2, BBS7 contains 672 amino acids and is expressed at low to moderate levels in most human tissues, BBSL1 was re-named BBS7, Five BBS proteins encode basal body or cilia proteins, and congenital heart defects, and developmental delay, hypertension, hypogenitalism, photoreceptor degeneration, polydactyly, renal abnormalities, suggesting that BBS is a ciliary dysfunction disorder, whereas BBS2L2 independently funcitons as BBS1, Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
625, 650nm/670nm |
| Synonyms: |
BBS8 RP51 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
BBS8/TTC8 Conjugated |
| Short name: |
Conjugated, BBS8/TTC8 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy5 |
| Alternative name: |
cyanine 5 coupled, BBS8/tetratricopeptide repeat domain 8 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cytoplasm, TTC8 and IDBG-15274 and ENSG00000165533 and 123016, TTC8 and IDBG-646921 and ENSBTAG00000030432 and 615652, Ttc8 and IDBG-163183 and ENSMUSG00000021013 and 76260, protein binding, this GO :0001103 and RNA polymerase II repressing transcription factor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005929 and cilium and cellular component this GO :0007411 and axon guidance and biological process this GO :0007608 and sensory perception of smell and biological process this GO :0015031 and protein transport and biological process this GO :0021772 and olfactory bulb development and biological process this GO :0032391 and photoreceptor connecting cilium and cellular component this GO :0032880 and regulation of protein localization and biological process this GO :0034464 and BBSome and cellular component this GO :0035058 and nonmotile primary cilium assembly and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0036064 and ciliary basal body and cellular component this GO :0042384 and cilium assembly and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0048560 and establishment of anatomical structure orientation and biological process this GO :0050893 and sensory processing and biological process this GO :0060170 and ciliary membrane and cellular component this GO :0060219 and camera-type eye photoreceptor cell differentiation and biological process this GO :0061326 and renal tubule development and biological process, this GO :0001103 : RNA polymerase II repressing transcription factor binding, this GO :0001103 : RNA polymerase II repressing transcription factor binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, tetratricopeptide repeat domain 8 |
| Identity: |
20087 |
| Gene: |
TTC8 |
More about : TTC8 |
| Long gene name: |
tetratricopeptide repeat domain 8 |
| Locus: |
14q31, 3 |
| Discovery year: |
2002-12-17 |
| GenBank acession: |
AK093891 |
| Entrez gene record: |
123016 |
| Pubmed identfication: |
14520415 20451172 |
| RefSeq identity: |
NM_144596 |
| Classification: |
Bardet-Biedl syndrome associated Tetratricopeptide repeat domain containing BBSome |
| Havana BLAST/BLAT: |
OTTHUMG00000170884 |