| Long name: |
FITC Conjugated, CADPS2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CADPS2 |
| Specificity: |
This is a highly specific antibody against CADPS2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CADPS2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Both CAPS-1 and CAPS-2 are expressed primarily in the brain where they regulate the secretion of various substances, CAPS proteins help to regulate cell fate during neuronal development, CAPS-1 is thought to regulate catecholamine release from neuronal cells, Defects in the genes encoding CAPS-1 and CAPS-2 are implicated in impaired cerebral development and autism, The CAPS proteins contain a PH domain that is essential for regulation of exocytosis, Through their regulation of neurotrophin release from granule cells, as well as regulation of phospholipid binding, while CAPS-2 is thought to regulate release of both brain-derived neurotrophic factor and neurotrophin-3 from granule cells, Calcium-dependent secretion activators (CAPS-1 and CAPS-2) are calcium-binding proteins that direct neurotransmitter and neuropeptide-filled vesicles to the cell membrane for secretory granule exocytosis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CAPS2 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CADPS2 Conjugated |
| Short name: |
FITC Conjugated, CADPS2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Ca+and-dependent secretion activator 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CADPS2 and IDBG-38565 and ENSG00000081803 and 93664, CADPS2 and IDBG-634757 and ENSBTAG00000005110 and 519444, Cadps2 and IDBG-129779 and ENSMUSG00000017978 and 320405, Cell surfaces, metal ion binding, this GO :0005515 and protein binding and molecular function this GO :0008289 and lipid binding and molecular function this GO :0009267 and cellular response to starvation and biological process this GO :0015031 and protein transport and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016082 and synaptic vesicle priming and biological process this GO :0030054 and cell junction and cellular component this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0042734 and presynaptic membrane and cellular component this GO :0045211 and postsynaptic membrane and cellular component this GO :0045921 and positive regulation of exocytosis and biological process this GO :0046872 and metal ion binding and molecular function, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008289 : lipid binding and also this GO :0046872 : metal ion binding, this GO :0008289 : lipid binding, this GO :0046872 : metal ion binding, Ca++-dependent secretion activator 2 |
| Identity: |
16018 |
| Gene: |
CADPS2 |
More about : CADPS2 |
| Long gene name: |
calcium dependent secretion activator 2 |
| Synonyms gene name: |
Ca++-dependent activator protein for secretion 2 Ca2+ dependent secretion activator 2 |
| Locus: |
7q31, 32 |
| Discovery year: |
2001-07-12 |
| Entrez gene record: |
93664 |
| RefSeq identity: |
NM_017954 |
| Classification: |
Pleckstrin homology domain containing C2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000157093 |