| Long name: |
CADPS2 Primary Polyclonal Antibody |
| Also known as: |
CADPS2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CADPS2 |
| Specificity: |
This is a highly specific antibody against CADPS2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CADPS2 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Both CAPS-1 and CAPS-2 are expressed primarily in the brain where they regulate the secretion of various substances, CAPS proteins help to regulate cell fate during neuronal development, CAPS-1 is thought to regulate catecholamine release from neuronal cells, Defects in the genes encoding CAPS-1 and CAPS-2 are implicated in impaired cerebral development and autism, The CAPS proteins contain a PH domain that is essential for regulation of exocytosis, Through their regulation of neurotrophin release from granule cells, as well as regulation of phospholipid binding, while CAPS-2 is thought to regulate release of both brain-derived neurotrophic factor and neurotrophin-3 from granule cells, Calcium-dependent secretion activators (CAPS-1 and CAPS-2) are calcium-binding proteins that direct neurotransmitter and neuropeptide-filled vesicles to the cell membrane for secretory granule exocytosis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CAPS2, CAPS2_HUMAN, Calcium-dependent activator protein for secretion 2, Calcium-dependent secretion activator 2, Cadps2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CADPS2 |
| Short name: |
CADPS2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Ca+and-dependent secretion activator 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CADPS2 and IDBG-38565 and ENSG00000081803 and 93664, CADPS2 and IDBG-634757 and ENSBTAG00000005110 and 519444, Cadps2 and IDBG-129779 and ENSMUSG00000017978 and 320405, Cell surfaces, metal ion binding, this GO :0005515 and protein binding and molecular function this GO :0008289 and lipid binding and molecular function this GO :0009267 and cellular response to starvation and biological process this GO :0015031 and protein transport and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016082 and synaptic vesicle priming and biological process this GO :0030054 and cell junction and cellular component this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0042734 and presynaptic membrane and cellular component this GO :0045211 and postsynaptic membrane and cellular component this GO :0045921 and positive regulation of exocytosis and biological process this GO :0046872 and metal ion binding and molecular function, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008289 : lipid binding and also this GO :0046872 : metal ion binding, this GO :0008289 : lipid binding, this GO :0046872 : metal ion binding, Ca++-dependent secretion activator 2 |
| Identity: |
16018 |
| Gene: |
CADPS2 |
More about : CADPS2 |
| Long gene name: |
calcium dependent secretion activator 2 |
| Synonyms gene name: |
Ca++-dependent activator protein for secretion 2 Ca2+ dependent secretion activator 2 |
| Synonyms: |
CAPS2 |
| Locus: |
7q31, 32 |
| Discovery year: |
2001-07-12 |
| Entrez gene record: |
93664 |
| RefSeq identity: |
NM_017954 |
| Classification: |
Pleckstrin homology domain containing C2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000157093 |