| Long name: |
ALEXA FLUOR 350 Conjugated, Torsin B Polyclonal Antibody |
| Also known as: |
Anti-Torsin B PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Torsin B |
| Specificity: |
This is a highly specific antibody against Torsin B |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Torsin B |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Defects in the gene encoding TorsinB are associated with torsion dystonia, Expressed in a variety of tissues with particularly high levels in adult brain, TorsinB contains two PKC (protein kinase C) phosphorylations sites, TorsinB is thought to function as a molecular chaperone that assists in the conformational folding of membrane and secreted proteins, TorsinB plays a key role in postnatal developmental events and is essential for proper neurological development, Via its ability to regulate protein folding, a related family member, an autosomal dominant neurological disorder that is characterized by debilitating muscle contractions throughout the body, one ATP binding domain and several conserved cysteines and shares 69% amino acid identity with TorsinA, TorsinB is a 336 amino acid protein that localizes to the lumen of endoplasmic reticulum and belongs to the Torsin family |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
DQ1 MGC4386 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
Torsin B |
| Short name: |
Torsin B Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, Torsin B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11995 |
| Gene: |
TOR1B |
More about : TOR1B |
| Long gene name: |
torsin family 1 member B |
| Synonyms gene name: |
member B (torsin B) , torsin family 1 |
| Synonyms name: |
torsin B |
| Locus: |
9q34, 11 |
| Discovery year: |
2000-02-17 |
| GenBank acession: |
AF007872 |
| Entrez gene record: |
27348 |
| Pubmed identfication: |
9288096 10644435 |
| RefSeq identity: |
NM_014506 |
| Havana BLAST/BLAT: |
OTTHUMG00000020795 |