| Long name: |
ALEXA FLUOR 555 Conjugated, Torsin A Polyclonal Antibody |
| Also known as: |
Anti-Torsin A PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Torsin A |
| Specificity: |
This is a highly specific antibody against Torsin A |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Torsin A |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Early-onset torsion dystonia is a movement disorder, Symptoms are believed to result from altered neuronal communication in the basal ganglia, The gene which encodes TorsinA has high homology to three additional mammalian genes and a nematode gene and distal similarity to the family of heat-shock proteins and the Clp protease family, The gene which encodes TorsinA maps to human chromosome 9q34, The proteins display cytoplasmic distribution, TorsinA comprises 332 amino acids, TorsinA is widely expressed throughout the mouse central nervous system and is detected in the majority of neurons in nearly all regions, TorsinA often performs chaperone-like functions that assist in the assembly, although in some types of neurons localization is perinuclear, characterized by twisting muscle contractures, has been identified as the cause of one form of autosomal dominantly inherited dystonia, operation, or dis-assembly of protein complexes, that begins in childhood, which codes for TorsinA, A mutation of the DYT1 gene |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Synonyms: |
FLJ14771 TORP1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
Torsin A |
| Short name: |
Torsin A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, Torsin A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11996 |
| Gene: |
TOR2A |
More about : TOR2A |
| Long gene name: |
torsin family 2 member A |
| Synonyms gene name: |
member A , torsin family 2 |
| Locus: |
9q34, 11 |
| Discovery year: |
2000-02-17 |
| GenBank acession: |
AA873275 |
| Entrez gene record: |
27433 |
| Pubmed identfication: |
10644435 |
| RefSeq identity: |
NM_130459 |
| Havana BLAST/BLAT: |
OTTHUMG00000020706 |