Cyclin D2 Antibody, ALEXA FLUOR 488

Catalog number:	bs-1148R-A488 Buy Now
Price:	Ask price €
Supplier:	accurate-monoclonals
Product name:	Cyclin D2 Antibody, ALEXA FLUOR 488
Quantity:	1 vial
Related search:	cyclin antibody fluor antibodies gene dcdk deg

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Long name:	ALEXA FLUOR 488 Conjugated, Cyclin D2 Polyclonal Antibody
Also known as:	Anti-Cyclin D2 PAb ALEXA FLUOR 488
Category:	Conjugated Primary Antibodies
Conjugated with:	488, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Cyclin D2
Specificity:	This is a highly specific antibody against Cyclin D2
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	150-200/288
Subcellular location:	Membrane bound, Nucleus, Cytoplasm
Source:	This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Cyclin D2
Gene ID Number:	894
Swiss Prot:	P30279
Tested applications:	IF(ICC), IF(IHC-P)
Recommended dilutions:	IF(ICC)(1:50-200), IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Also substrate for SMAD3, Component of the ternary complex, Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals, Hypophosphorylates RB1 in early G(1) phase, Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase, cyclin D2/CDK4/CDKN1B, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity), Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	499nm/519nm
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Cyclin D2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Gene target:	Cyclin D2
Short name:	Cyclin D2 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 488
Alternative name:	ALEXA FLUOR 488, Cyclin D2 (Antibody to)
Alternative technique:	antibodies
Identity:	1583
Gene:	CCND2 | More about : CCND2
Long gene name:	cyclin D2
Synonyms name:	G1/S-specific cyclin D2
Locus:	12p13, 32
Discovery year:	1991-12-10
GenBank acession:	AF518005
Entrez gene record:	894
Pubmed identfication:	1386335
RefSeq identity:	NM_001759
Classification:	Cyclins
Havana BLAST/BLAT:	OTTHUMG00000168123

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