| Catalog number: | bs-0573R-A488 |
|---|---|
| Price: | Ask price € |
| Supplier: | accurate-monoclonals |
| Product name: | Cyclin E Antibody, ALEXA FLUOR 488 |
| Quantity: | 1 vial |
| Other quantities: | 100ul 332€ |
| Related search: |
| Long name: | ALEXA FLUOR 488 Conjugated, Cyclin E Polyclonal Antibody |
|---|---|
| Also known as: | Anti-Cyclin E PAb ALEXA FLUOR 488 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 488, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | Cyclin E |
| Specificity: | This is a highly specific antibody against Cyclin E |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 370-411/411 |
| Subcellular location: | Nucleus |
| Source: | KLH conjugated synthetic peptide derived from rat Cyclin E |
| Gene ID Number: | 25729 |
| Swiss Prot: | P39949 |
| Tested applications: | IF(IHC-P), FCM |
| Recommended dilutions: | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: | Rat, Mouse |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Cyclins function as regulators of CDK kinases, Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event, Overexpression of this gene has been observed in many tumors, The encoded protein has a 15 aa longer N-terminus, This cyclin forms a complex with and functions as a regulatory subunit of CDK2, This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase, This protein was found to associate with, Transcript Variant: This variant (1) contains a different 5' end region, Two additional splice variants were reported but detailed nucleotide sequence information is not yet available, Two alternatively spliced transcript variants of this gene, and be involved in, and thus may contribute to tumorigenesis, as compared to isoform 2, have been described, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), when compared to variant 2, which encode distinct isoforms, which includes an upstream in-frame translation start codon, which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB, which results in chromosome instability, whose activity is required for cell cycle G1/S transition, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle, The protein encoded by this gene belongs to the highly conserved cyclin family |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 499nm/519nm |
| Synonyms: | CYCLE, Ccne1, G1/S-specific cyclin-E1, Ccne |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Cyclin E Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | Alexa Fluor |
| Gene target: | Cyclin E |
| Short name: | Cyclin E Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 488 |
| Alternative name: | ALEXA FLUOR 488, Cyclin E (Antibody to) |
| Alternative technique: | antibodies |
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