Cyclin D1 Antibody, ALEXA FLUOR 488

Catalog number:	bs-0623R-A488 Buy Now
Price:	Ask price €
Supplier:	accurate-monoclonals
Product name:	Cyclin D1 Antibody, ALEXA FLUOR 488
Quantity:	1 vial
Related search:	cyclin alexa antibody fluor gene antibodies conjugated synonyms activity protein

More details Need more?:

Long name:	ALEXA FLUOR 488 Conjugated, Cyclin D1 Polyclonal Antibody
Also known as:	Anti-Cyclin D1 PAb ALEXA FLUOR 488
Category:	Conjugated Primary Antibodies
Conjugated with:	488, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Cyclin D1
Specificity:	This is a highly specific antibody against Cyclin D1
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen range:	70-120/295
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic peptide derived from mouse Cyclin D1
Gene ID Number:	12443
Swiss Prot:	P25322
Tested applications:	IF(ICC), IF(IHC-P), FCM
Recommended dilutions:	IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity:	Goat, Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Also substrate for SMAD3, Component of the ternary complex, Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals, Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner (By similarity), Hypophosphorylates RB1 in early G(1) phase, Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase, cyclin D1/CDK4/CDKN1B, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity, required for nuclear translocation and activity of the cyclin D-CDK4 complex, Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	499nm/519nm
Synonyms:	U21B31
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Cyclin D1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Gene target:	Cyclin D1
Short name:	Cyclin D1 Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 488
Alternative name:	ALEXA FLUOR 488, Cyclin D1 (Antibody to)
Alternative technique:	antibodies
Identity:	1582
Gene:	CCND1 | More about : CCND1
Long gene name:	cyclin D1
Synonyms gene:	BCL1 D11S287E PRAD1
Synonyms gene name:	cyclin D1 (PRAD1: parathyroid adenomatosis 1)
Synonyms name:	parathyroid adenomatosis 1 B-cell CLL/lymphoma 1 G1/S-specific cyclin D1
Locus:	11q13, 3
Discovery year:	1991-06-06
GenBank acession:	Z23022
Entrez gene record:	595
Pubmed identfication:	1826542 1833066
RefSeq identity:	NM_053056
Classification:	Cyclins
Havana BLAST/BLAT:	OTTHUMG00000167877
Locus Specific Databases:	LRG_990

• #cyclin
• #alexa
• #antibody
• #fluor
• #gene
• #antibodies
• #conjugated
• #synonyms
• #activity
• #protein