| Long name: |
FITC Conjugated, NGBR/Nogo B receptor Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NGBR/Nogo B receptor |
| Specificity: |
This is a highly specific antibody against NGBR/Nogo B receptor |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human NGBR/Nogo B receptor |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
-B and -C, Knockdown of NgBR mRNA leads to decreased NPC2 levels, NgBR (Nogo-B receptor), NgBR also enhances Niemann-Pick type C2 protein (NPC2) stabilization, NgBR is involved in the regulation of vascular remodeling and angiogenesis, Nogo exists in three different splice forms, Nogo is expressed by oligodendrocytes but not by Schwann cells and associates primarily with the endoplasmic reticulum, Nogo-A, Through this interaction, also known as nuclear undecaprenyl pyrophosphate synthase 1 homolog, and inhibits the spreading of 3T3 fibroblasts, induces collapse of growth cones of chick dorsal root ganglion cells, is a 293 amino acid single-pass type I membrane protein that acts as a specific receptor for the amino-terminus of Nogo-B, which results in the hallmarks of NPC2 mutation: increased intracellular cholesterol accumulation and a loss of sterol sensing, Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
MGC7199 NgBR TANGO14 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
NGBR/Nogo B receptor Conjugated |
| Short name: |
FITC Conjugated, NGBR/Nogo B receptor Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, NGBR/Nogo B receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21042 |
| Gene: |
NUS1 |
More about : NUS1 |
| Long gene name: |
NUS1 dehydrodolichyl diphosphate synthase subunit |
| Synonyms gene: |
C6orf68 |
| Synonyms gene name: |
cerevisiae) , chromosome 6 open reading frame 68 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S |
| Synonyms name: |
Nogo-B receptor transport and golgi organization 14 homolog (Drosophila) |
| Locus: |
6q22, 1 |
| Discovery year: |
2003-05-08 |
| GenBank acession: |
BC013026 |
| Entrez gene record: |
116150 |
| Pubmed identfication: |
25066056 |
| RefSeq identity: |
NM_138459 |
| Havana BLAST/BLAT: |
OTTHUMG00000015458 |