| Long name: |
NGBR/Nogo B receptor Primary Polyclonal Antibody |
| Also known as: |
NGBR/Nogo B receptor PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
NGBR/Nogo B receptor |
| Specificity: |
This is a highly specific antibody against NGBR/Nogo B receptor |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NGBR/Nogo B receptor |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
-B and -C, Knockdown of NgBR mRNA leads to decreased NPC2 levels, NgBR (Nogo-B receptor), NgBR also enhances Niemann-Pick type C2 protein (NPC2) stabilization, NgBR is involved in the regulation of vascular remodeling and angiogenesis, Nogo exists in three different splice forms, Nogo is expressed by oligodendrocytes but not by Schwann cells and associates primarily with the endoplasmic reticulum, Nogo-A, Through this interaction, also known as nuclear undecaprenyl pyrophosphate synthase 1 homolog, and inhibits the spreading of 3T3 fibroblasts, induces collapse of growth cones of chick dorsal root ganglion cells, is a 293 amino acid single-pass type I membrane protein that acts as a specific receptor for the amino-terminus of Nogo-B, which results in the hallmarks of NPC2 mutation: increased intracellular cholesterol accumulation and a loss of sterol sensing, Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
NGBR, NGBR_HUMAN, NUS1, nuclear undecaprenyl pyrophosphate synthase 1 homolog, C6orf68 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
NGBR/Nogo B receptor |
| Short name: |
NGBR/Nogo B receptor Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
NGBR/Nogo B receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21042 |
| Gene: |
NUS1 |
More about : NUS1 |
| Long gene name: |
NUS1 dehydrodolichyl diphosphate synthase subunit |
| Synonyms gene: |
C6orf68 |
| Synonyms gene name: |
cerevisiae) , chromosome 6 open reading frame 68 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S |
| Synonyms: |
MGC7199 NgBR TANGO14 |
| Synonyms name: |
Nogo-B receptor transport and golgi organization 14 homolog (Drosophila) |
| Locus: |
6q22, 1 |
| Discovery year: |
2003-05-08 |
| GenBank acession: |
BC013026 |
| Entrez gene record: |
116150 |
| Pubmed identfication: |
25066056 |
| RefSeq identity: |
NM_138459 |
| Havana BLAST/BLAT: |
OTTHUMG00000015458 |