| Long name: |
ALEXA FLUOR 594 Conjugated, NGBR/Nogo B receptor Polyclonal Antibody |
| Also known as: |
Anti-NGBR/Nogo B receptor PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
NGBR/Nogo B receptor |
| Specificity: |
This is a highly specific antibody against NGBR/Nogo B receptor |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NGBR/Nogo B receptor |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
-B and -C, Knockdown of NgBR mRNA leads to decreased NPC2 levels, NgBR (Nogo-B receptor), NgBR also enhances Niemann-Pick type C2 protein (NPC2) stabilization, NgBR is involved in the regulation of vascular remodeling and angiogenesis, Nogo exists in three different splice forms, Nogo is expressed by oligodendrocytes but not by Schwann cells and associates primarily with the endoplasmic reticulum, Nogo-A, Through this interaction, also known as nuclear undecaprenyl pyrophosphate synthase 1 homolog, and inhibits the spreading of 3T3 fibroblasts, induces collapse of growth cones of chick dorsal root ganglion cells, is a 293 amino acid single-pass type I membrane protein that acts as a specific receptor for the amino-terminus of Nogo-B, which results in the hallmarks of NPC2 mutation: increased intracellular cholesterol accumulation and a loss of sterol sensing, Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MGC7199 NgBR TANGO14 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target: |
NGBR/Nogo B receptor |
| Short name: |
NGBR/Nogo B receptor Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, NGBR/Nogo B receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
21042 |
| Gene: |
NUS1 |
More about : NUS1 |
| Long gene name: |
NUS1 dehydrodolichyl diphosphate synthase subunit |
| Synonyms gene: |
C6orf68 |
| Synonyms gene name: |
cerevisiae) , chromosome 6 open reading frame 68 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S |
| Synonyms name: |
Nogo-B receptor transport and golgi organization 14 homolog (Drosophila) |
| Locus: |
6q22, 1 |
| Discovery year: |
2003-05-08 |
| GenBank acession: |
BC013026 |
| Entrez gene record: |
116150 |
| Pubmed identfication: |
25066056 |
| RefSeq identity: |
NM_138459 |
| Havana BLAST/BLAT: |
OTTHUMG00000015458 |