| Long name: |
FITC Conjugated, DCAMKL1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DCAMKL1 |
| Specificity: |
This is a highly specific antibody against DCAMKL1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DCAMKL1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
All three proteins are highly expressed in developing brain and may function together to regulate microtubules involved in neuronal migration, Genetic analysis has identified two proteins that are mutated in some cases of lissencephaly, In addition, LIS1 displays sequence homology to ?subunits of heterotrimeric G proteins, The DCAMKL1 protein encodes a functional kinase that is capable of phosphorylating myelin basic protein and itself, and doublecortin contains a consensus Abl phosphorylation site, but its kinase activity does not appear to affect its microtubule polymerization activity, designated lissencephaly-1 protein (LIS1) and doublecortin, manifesting as severe mental retardation, the DCAMKL1 (doublecortin-like and CAM kinase-like 1) protein shows homology to doublecortin, Lissencephaly (smooth brain) is an abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
KIAA0369 DCLK DCDC3A |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DCAMKL1 Conjugated |
| Short name: |
FITC Conjugated, DCAMKL1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, DCAMKL1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2700 |
| Gene: |
DCLK1 |
More about : DCLK1 |
| Long gene name: |
doublecortin like kinase 1 |
| Synonyms gene: |
DCAMKL1 |
| Synonyms gene name: |
doublecortin and CaM kinase-like 1 doublecortin-like kinase 1 |
| Locus: |
13q13, 3 |
| Discovery year: |
1999-02-22 |
| GenBank acession: |
AB002367 |
| Entrez gene record: |
9201 |
| Pubmed identfication: |
9747029 10036192 |
| RefSeq identity: |
NM_004734 |
| Classification: |
Doublecortin superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000016729 |