| Long name: |
DCAMKL1 Primary Polyclonal Antibody |
| Also known as: |
DCAMKL1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DCAMKL1 |
| Specificity: |
This is a highly specific antibody against DCAMKL1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DCAMKL1 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
All three proteins are highly expressed in developing brain and may function together to regulate microtubules involved in neuronal migration, Genetic analysis has identified two proteins that are mutated in some cases of lissencephaly, In addition, LIS1 displays sequence homology to ?subunits of heterotrimeric G proteins, The DCAMKL1 protein encodes a functional kinase that is capable of phosphorylating myelin basic protein and itself, and doublecortin contains a consensus Abl phosphorylation site, but its kinase activity does not appear to affect its microtubule polymerization activity, designated lissencephaly-1 protein (LIS1) and doublecortin, manifesting as severe mental retardation, the DCAMKL1 (doublecortin-like and CAM kinase-like 1) protein shows homology to doublecortin, Lissencephaly (smooth brain) is an abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Cpg16, DCLK1_HUMAN, Dcl, Dclk, Dclk1, Doublecortin domain-containing protein 3A, Doublecortin-like and CAM kinase-like 1, Doublecortin-like kinase 1, KIAA0369, Serine/threonine-protein kinase DCAMKL1, Serine/threonine-protein kinase DCLK1, Calcium/calmodulin-dependent protein kinase type I-like CPG16 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DCAMKL1 |
| Short name: |
DCAMKL1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DCAMKL1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2700 |
| Gene: |
DCLK1 |
More about : DCLK1 |
| Long gene name: |
doublecortin like kinase 1 |
| Synonyms gene: |
DCAMKL1 |
| Synonyms gene name: |
doublecortin and CaM kinase-like 1 doublecortin-like kinase 1 |
| Synonyms: |
KIAA0369 DCLK DCDC3A |
| Locus: |
13q13, 3 |
| Discovery year: |
1999-02-22 |
| GenBank acession: |
AB002367 |
| Entrez gene record: |
9201 |
| Pubmed identfication: |
9747029 10036192 |
| RefSeq identity: |
NM_004734 |
| Classification: |
Doublecortin superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000016729 |