| Long name: |
ALEXA FLUOR 488 Conjugated, DCAMKL1 Polyclonal Antibody |
| Also known as: |
Anti-DCAMKL1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DCAMKL1 |
| Specificity: |
This is a highly specific antibody against DCAMKL1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DCAMKL1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
All three proteins are highly expressed in developing brain and may function together to regulate microtubules involved in neuronal migration, Genetic analysis has identified two proteins that are mutated in some cases of lissencephaly, In addition, LIS1 displays sequence homology to ?subunits of heterotrimeric G proteins, The DCAMKL1 protein encodes a functional kinase that is capable of phosphorylating myelin basic protein and itself, and doublecortin contains a consensus Abl phosphorylation site, but its kinase activity does not appear to affect its microtubule polymerization activity, designated lissencephaly-1 protein (LIS1) and doublecortin, manifesting as severe mental retardation, the DCAMKL1 (doublecortin-like and CAM kinase-like 1) protein shows homology to doublecortin, Lissencephaly (smooth brain) is an abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
KIAA0369 DCLK DCDC3A |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the DCAMKL1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
DCAMKL1 |
| Short name: |
DCAMKL1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, DCAMKL1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2700 |
| Gene: |
DCLK1 |
More about : DCLK1 |
| Long gene name: |
doublecortin like kinase 1 |
| Synonyms gene: |
DCAMKL1 |
| Synonyms gene name: |
doublecortin and CaM kinase-like 1 doublecortin-like kinase 1 |
| Locus: |
13q13, 3 |
| Discovery year: |
1999-02-22 |
| GenBank acession: |
AB002367 |
| Entrez gene record: |
9201 |
| Pubmed identfication: |
9747029 10036192 |
| RefSeq identity: |
NM_004734 |
| Classification: |
Doublecortin superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000016729 |