| Long name: |
Biotin Conjugated, AANAT (Thr29) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
AANAT Thr29 |
| Specificity: |
This is a highly specific antibody against AANAT Thr29 |
| Modification: |
Phosphorylation |
| Modification site: |
Thr29 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from mouse AANAT around the phosphorylation site of Thr29 |
| Gene ID number: |
11298 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Arylalkylamine N-acetyltransferase may contribute a multifactorial genetic diseases such as altered behavior in sleep/wake cycle, It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland, Melatonin is essential for seasonal reproduction, This enzyme is rapidly inactivated when animals are exposed to light at night, This protein is 80% identical to sheep and rat AA-NAT, and influences activity and sleep, modulates the function of the circadian clock in the suprachiasmatic nucleus, Arylalkylamine N-acetyltransferase belongs to the superfamily of acetyltransferases |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
SNAT |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AANAT (Thr29) Conjugated |
| Short name: |
Conjugated, AANAT (Thr29) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, aralkylamine N-acetyltransferase (Thr29) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
14-3-3 protein binding, AANAT and IDBG-69711 and ENSG00000129673 and 15, Aanat and IDBG-214486 and ENSMUSG00000020804 and 11298, Cytoplasm, DSPS and SNAT, this GO :0004059 and aralkylamine N-acetyltransferase activity and molecular function this GO :0004060 and arylamine N-acetyltransferase activity and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006474 and N-terminal protein amino acid acetylation and biological process this GO :0007623 and circadian rhythm and biological process this GO :0008080 and N-acetyltransferase activity and molecular function this GO :0009416 and response to light stimulus and biological process this GO :0010043 and response to zinc ion and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0030187 and melatonin biosynthetic process and biological process this GO :0032868 and response to insulin and biological process this GO :0034097 and response to cytokine and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0034695 and response to prostaglandin E and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0046219 and indolalkylamine biosynthetic process and biological process this GO :0046688 and response to copper ion and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051412 and response to corticosterone and biological process this GO :0051591 and response to cAMP and biological process this GO :0051592 and response to calcium ion and biological process this GO :0071320 and cellular response to cAMP and biological process this GO :0071889 and 14-3-3 protein binding and molecular function, this GO :0004059 : aralkylamine N-acetyltransferase activity, this GO :0004059 : aralkylamine N-acetyltransferase activity and also this GO :0004060 : arylamine N-acetyltransferase activity and also this GO :0008080 : N-acetyltransferase activity and also this GO :0071889 : 14-3-3 protein binding, this GO :0004060 : arylamine N-acetyltransferase activity, this GO :0008080 : N-acetyltransferase activity, this GO :0071889 : 14-3-3 protein binding, aralkylamine N-acetyltransferase |
| Identity: |
19 |
| Gene: |
AANAT |
More about : AANAT |
| Long gene name: |
aralkylamine N-acetyltransferase |
| Synonyms gene name: |
arylalkylamine N-acetyltransferase |
| Synonyms name: |
serotonin N-acetyltransferase |
| Locus: |
17q25, 1 |
| Discovery year: |
1995-12-13 |
| GenBank acession: |
U40347 |
| Entrez gene record: |
15 |
| Pubmed identfication: |
8661026 |
| RefSeq identity: |
NM_001088 |
| Classification: |
GCN5 related N-acetyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000180179 |