| Long name: |
FITC Conjugated, Synaptic Ras-GAP 1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SynGAP |
| Specificity: |
This is a highly specific antibody against SynGAP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Synaptic Ras-GAP 1/SynGAP |
| Gene ID number: |
8831 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors, Its activity is inhibited by phosphorylation by CaMKII, SynGAP (for synaptic GTPase activating protein), SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins, SynGAP may be involved in the regulation of BDNF as well as Ras signaling, a novel synaptic RasGAP, are involved in the organization of synaptic structure, hippocampus and olfactory bulb, is a brain-specific protein abundant in the cortex, which are known to bind to and cluster various membrane proteins, which could result in the activation of the MAP kinase pathway, The PSD-95/SAP 90 family of proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
GAP CM-AVM p120GAP p120RASGAP p120 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Synaptic Ras-GAP 1 Conjugated |
| Short name: |
FITC Conjugated, Synaptic Ras-GAP 1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Synaptic Ras-GAP 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9871 |
| Gene: |
RASA1 |
More about : RASA1 |
| Long gene name: |
RAS p21 protein activator 1 |
| Synonyms gene: |
RASA |
| Synonyms gene name: |
RAS p21 protein activator (GTPase activating protein) 1 |
| Synonyms name: |
capillary malformation-arteriovenous malformation p120 RAS GTPase activating protein |
| Locus: |
5q14, 3 |
| Discovery year: |
1989-06-30 |
| Entrez gene record: |
5921 |
| Pubmed identfication: |
15917201 |
| RefSeq identity: |
NM_002890 |
| Classification: |
Pleckstrin homology domain containing SH2 domain containing C2 and RasGAP domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000162605 |
| Locus Specific Databases: |
SH2base: Database for pathogenic SH2 domain mutations |