| Long name: |
Cy3 Conjugated, Synaptic Ras-GAP 1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
cy3 conjugation kit |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SynGAP |
| Specificity: |
This is a highly specific antibody against SynGAP |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Synaptic Ras-GAP 1/SynGAP |
| Gene ID number: |
8831 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
It represents one of three classes of mammalian RasGAPs and is specifically localized to excitatory synapses possessing NMDA receptors, Its activity is inhibited by phosphorylation by CaMKII, SynGAP (for synaptic GTPase activating protein), SynGAP interacts with all three PDZ domains within PSD-95/ SAP 90 proteins, SynGAP may be involved in the regulation of BDNF as well as Ras signaling, a novel synaptic RasGAP, are involved in the organization of synaptic structure, hippocampus and olfactory bulb, is a brain-specific protein abundant in the cortex, which are known to bind to and cluster various membrane proteins, which could result in the activation of the MAP kinase pathway, The PSD-95/SAP 90 family of proteins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
512, 550nm/570, 615nm |
| Synonyms: |
GAP CM-AVM p120GAP p120RASGAP p120 |
| Properties: |
1 of the Synaptic Ras-GAP 1 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Synaptic Ras-GAP 1 Conjugated |
| Short name: |
Conjugated, Synaptic Ras-GAP 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy3 |
| Alternative name: |
cyanine 3 coupled, Synaptic Ras-GAP 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9871 |
| Gene: |
RASA1 |
More about : RASA1 |
| Long gene name: |
RAS p21 protein activator 1 |
| Synonyms gene: |
RASA |
| Synonyms gene name: |
RAS p21 protein activator (GTPase activating protein) 1 |
| Synonyms name: |
capillary malformation-arteriovenous malformation p120 RAS GTPase activating protein |
| Locus: |
5q14, 3 |
| Discovery year: |
1989-06-30 |
| Entrez gene record: |
5921 |
| Pubmed identfication: |
15917201 |
| RefSeq identity: |
NM_002890 |
| Classification: |
Pleckstrin homology domain containing SH2 domain containing C2 and RasGAP domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000162605 |
| Locus Specific Databases: |
SH2base: Database for pathogenic SH2 domain mutations |