| Long name: |
FITC Conjugated, ICA1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ICA1 |
| Specificity: |
This is a highly specific antibody against ICA1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human ICA1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
As catalysts of the reversible hydration of carbon dioxide, CA I localizes to the cytoplasm and research indicates that a severe deficiency of CA I does not result in any obvious hematological or renal consequences, Genes in the ?carbonic anhydrase family encode either active carbonic anhydrase isozymes or æ, Human CA I (CA1) is encoded by the CA1 gene, acid-base balance, also designated carbonate dehydratases or carbonate hydrolyases, bone resorption and calcification as well as the formation of aqueous humor, cerebrospinal fluid, form a large family of genes that encode zinc metalloenzymes of great physiologic importance, including respiration, saliva and gastric acid, these enzymes participate in a variety of biologic processes, which maps to a region on chromosome 8 that harbors a cluster of CA genes, Carbonic anhydrases (CAs), catalytic?(devoid of CO2 hydration activity) carbonic anhydrase-related proteins, ³ |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
ICAp69 ICA69 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ICA1 Conjugated |
| Short name: |
FITC Conjugated, ICA1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
69kDa (Antibody to), fluorecein coupled, islet cell autoantigen 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
69kDa, BT, Cell surfaces, ICA1 and IDBG-8551 and ENSG00000003147 and 3382, ICA69 and ICAp69, Ica1 and IDBG-128452 and ENSMUSG00000062995 and 15893, protein domain specific binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0003674 and molecular function and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006836 and neurotransmitter transport and biological process this GO :0019904 and protein domain specific binding and molecular function this GO :0030054 and cell junction and cellular component this GO :0030658 and transport vesicle membrane and cellular component this GO :0030667 and secretory granule membrane and cellular component this GO :0030672 and synaptic vesicle membrane and cellular component, this GO :0003674 : molecular_function, this GO :0003674 : molecular_function and also this GO :0019904 : protein domain specific binding, this GO :0019904 : protein domain specific binding, 35115 and IDBG-629525 and ENSBTAG00000000799 and 535346, islet cell autoantigen 1 |
| Identity: |
5343 |
| Gene: |
ICA1 |
More about : ICA1 |
| Long gene name: |
islet cell autoantigen 1 |
| Synonyms gene name: |
69kDa , islet cell autoantigen 1 (69kD) islet cell autoantigen 1 |
| Locus: |
7p21, 3 |
| Discovery year: |
1992-08-24 |
| Entrez gene record: |
3382 |
| Pubmed identfication: |
7918678 8777998 |
| RefSeq identity: |
NM_004968 |
| Classification: |
Classical BAR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000152008 |