| Long name: |
ICA1 Primary Polyclonal Antibody |
| Also known as: |
ICA1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ICA1 |
| Specificity: |
This is a highly specific antibody against ICA1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ICA1 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
As catalysts of the reversible hydration of carbon dioxide, CA I localizes to the cytoplasm and research indicates that a severe deficiency of CA I does not result in any obvious hematological or renal consequences, Genes in the ?carbonic anhydrase family encode either active carbonic anhydrase isozymes or æ, Human CA I (CA1) is encoded by the CA1 gene, acid-base balance, also designated carbonate dehydratases or carbonate hydrolyases, bone resorption and calcification as well as the formation of aqueous humor, cerebrospinal fluid, form a large family of genes that encode zinc metalloenzymes of great physiologic importance, including respiration, saliva and gastric acid, these enzymes participate in a variety of biologic processes, which maps to a region on chromosome 8 that harbors a cluster of CA genes, Carbonic anhydrases (CAs), catalytic?(devoid of CO2 hydration activity) carbonic anhydrase-related proteins, ³ |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Diabetes mellitus type I autoantigen, ICA 1, ICA1, ICA69, ICA69_HUMAN, ICAp69, Islet cell autoantigen 1, Islet cell autoantigen 1 69kD, Islet cell autoantigen 1 69kDa, Islet cell autoantigen 1 isoform, Islet cell autoantigen p69, OTTHUMP00000200933, OTTHUMP00000200934, OTTHUMP00000200941, OTTHUMP00000200993, p69, 69 kDa islet cell autoantigen |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ICA1 |
| Short name: |
ICA1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
69kDa (Antibody to), islet cell autoantigen 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
69kDa, BT, Cell surfaces, ICA1 and IDBG-8551 and ENSG00000003147 and 3382, ICA69 and ICAp69, Ica1 and IDBG-128452 and ENSMUSG00000062995 and 15893, protein domain specific binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0003674 and molecular function and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006836 and neurotransmitter transport and biological process this GO :0019904 and protein domain specific binding and molecular function this GO :0030054 and cell junction and cellular component this GO :0030658 and transport vesicle membrane and cellular component this GO :0030667 and secretory granule membrane and cellular component this GO :0030672 and synaptic vesicle membrane and cellular component, this GO :0003674 : molecular_function, this GO :0003674 : molecular_function and also this GO :0019904 : protein domain specific binding, this GO :0019904 : protein domain specific binding, 35115 and IDBG-629525 and ENSBTAG00000000799 and 535346, islet cell autoantigen 1 |
| Identity: |
5343 |
| Gene: |
ICA1 |
More about : ICA1 |
| Long gene name: |
islet cell autoantigen 1 |
| Synonyms gene name: |
69kDa , islet cell autoantigen 1 (69kD) islet cell autoantigen 1 |
| Synonyms: |
ICAp69 ICA69 |
| Locus: |
7p21, 3 |
| Discovery year: |
1992-08-24 |
| Entrez gene record: |
3382 |
| Pubmed identfication: |
7918678 8777998 |
| RefSeq identity: |
NM_004968 |
| Classification: |
Classical BAR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000152008 |