| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ICA1 |
| Specificity: |
This antibody reacts specifically with ICA1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ICA1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
As catalysts of the reversible hydration of carbon dioxide, CA I localizes to the cytoplasm and research indicates that a severe deficiency of CA I does not result in any obvious hematological or renal consequences, Genes in the ?carbonic anhydrase family encode either active carbonic anhydrase isozymes or æ, Human CA I (CA1) is encoded by the CA1 gene, acid-base balance, also designated carbonate dehydratases or carbonate hydrolyases, bone resorption and calcification as well as the formation of aqueous humor, cerebrospinal fluid, form a large family of genes that encode zinc metalloenzymes of great physiologic importance, including respiration, saliva and gastric acid, these enzymes participate in a variety of biologic processes, which maps to a region on chromosome 8 that harbors a cluster of CA genes, Carbonic anhydrases (CAs), catalytic?(devoid of CO2 hydration activity) carbonic anhydrase-related proteins, ³ |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ICAp69 ICA69 |
| Also known as: |
ICA1 Polyclonal Antibody |
| Other name: |
Anti-ICA1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ICA1 |
| Short name: |
Anti-ICA1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
69kDa (polyclonal), ALEXA Fluor 594, antibody to-islet cell autoantigen 1 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
69kDa, BT, Cell surfaces, ICA1 and IDBG-8551 and ENSG00000003147 and 3382, ICA69 and ICAp69, Ica1 and IDBG-128452 and ENSMUSG00000062995 and 15893, protein domain specific binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0003674 and molecular function and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006836 and neurotransmitter transport and biological process this GO :0019904 and protein domain specific binding and molecular function this GO :0030054 and cell junction and cellular component this GO :0030658 and transport vesicle membrane and cellular component this GO :0030667 and secretory granule membrane and cellular component this GO :0030672 and synaptic vesicle membrane and cellular component, this GO :0003674 : molecular_function, this GO :0003674 : molecular_function and also this GO :0019904 : protein domain specific binding, this GO :0019904 : protein domain specific binding, 35115 and IDBG-629525 and ENSBTAG00000000799 and 535346, islet cell autoantigen 1 |
| Identity: |
5343 |
| Gene: |
ICA1 |
More about : ICA1 |
| Long gene name: |
islet cell autoantigen 1 |
| Synonyms gene name: |
69kDa , islet cell autoantigen 1 (69kD) islet cell autoantigen 1 |
| Locus: |
7p21, 3 |
| Discovery year: |
1992-08-24 |
| Entrez gene record: |
3382 |
| Pubmed identfication: |
7918678 8777998 |
| RefSeq identity: |
NM_004968 |
| Classification: |
Classical BAR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000152008 |